Overview

  • Product name

  • Description

    Rabbit polyclonal to Slc6a6/Taut
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Slc6a6/Taut aa 570-620.
    Sequence:

    G PFLVRVKYLL TPREPNRWAV EREGATPYNS RTVMNGALVK PTHIIVETMM

  • Positive control

    • Human lung carcinoma tissue.
  • General notes

     This product was previously labelled as Slc6a6

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab111167 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab111167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake.
  • Tissue specificity

    Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
  • Sequence similarities

    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
  • Post-translational
    modifications

    Down-regulated upon Ser-322 phosphorylation.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC10619 antibody
    • MGC131729 antibody
    • OTTHUMP00000208177 antibody
    • OTTHUMP00000208180 antibody
    • SC6A6_HUMAN antibody
    • SLC6A6 antibody
    • Sodium- and chloride-dependent taurine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 antibody
    • Solute carrier family 6 member 6 antibody
    • TAUT antibody
    see all

Images

  • ab111167 at 1/50 dilution staining Slc6a6/Taut in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with synthesized peptide.

References

ab111167 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab111167.
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