Overview

  • Product name

  • Description

    Rabbit polyclonal to Slc6a6/Taut
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous levels of total Slc6a6/Taut protein.

  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human Slc6a6/Taut (internal sequence). The exact sequence is proprietary.
    Database link: P31641

  • Positive control

    • COLO205 cell extract; Human lung carcinoma tissue.
  • General notes

     This product was previously labelled as Slc6a6

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab196821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB 1/500 - 1/3000. Predicted molecular weight: 70 kDa.

Target

  • Function

    Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake.
  • Tissue specificity

    Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
  • Sequence similarities

    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
  • Post-translational
    modifications

    Down-regulated upon Ser-322 phosphorylation.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC10619 antibody
    • MGC131729 antibody
    • OTTHUMP00000208177 antibody
    • OTTHUMP00000208180 antibody
    • SC6A6_HUMAN antibody
    • SLC6A6 antibody
    • Sodium- and chloride-dependent taurine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 antibody
    • Solute carrier family 6 member 6 antibody
    • TAUT antibody
    see all

Images

  • All lanes : Anti-Slc6a6/Taut antibody (ab196821) at 1/500 dilution

    Lane 1 : COLO205 cell extract
    Lane 2 : COLO205 cell extract with treated with synthesized peptide

    Predicted band size: 70 kDa

  • Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue labeling Slc6a6/Taut with ab196821 at 1/50 (left) and (right) synthesized peptide.

References

ab196821 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab196821.
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