Overview

  • Product name

  • Description

    Goat polyclonal to SLC6A8
  • Host species

    Goat
  • Specificity

    ab130132 is expected to recognize all reported isoforms (NP_005620.1; NP_001136277.1; NP_001136278.1).
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Human, Pig, Chinese hamster
  • Immunogen

    Synthetic peptide:

    ASLANLTCDQLADRR

    , corresponding to internal sequence amino acids 193-207 of Human SLC6A8 (NP_005620.1; NP_001136277.1; NP_001136278.1).

  • Positive control

    • Mouse Heart, Kidney and Skeletal muscle lysates.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab130132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 70 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Required for the uptake of creatine in muscles and brain.
  • Tissue specificity

    Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
  • Involvement in disease

    Cerebral creatine deficiency syndrome 1
  • Sequence similarities

    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • SLC6A 8 antibody
    • SLC6A8 antibody
    • Creatine transporter 1 antibody
    • Creatine transporter SLC6A8 antibody
    • CRT antibody
    • CRTR antibody
    • CT 1 antibody
    • CT1 antibody
    • MGC87396 antibody
    • SC6A8_HUMAN antibody
    • Slc6a8 antibody
    • Sodium and chloride-dependent creatine transporter 1 antibody
    • Sodium- and chloride-dependent creatine transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
    • Solute carrier family 6 member 8 antibody
    see all

Images

  • Anti-SLC6A8 antibody (ab130132) at 0.1 µg/ml + Mouse Heart lysate at 35 µg

    Predicted band size: 70 kDa

  • Immunohistochemical analysis of paraffin embedded Human kidney staining SLC6A8 at 5µg/ml.Steamed antigen retrieval with citrate buffer pH 6, AP-staining

References

ab130132 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab130132.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up