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    slc6a8-antibody-ab137198.pdf

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Signal Transduction Metabolism Plasma Membrane Channels
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Anti-SLC6A8 antibody (ab137198)

  • Datasheet
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Western blot - Anti-SLC6A8 antibody (ab137198)

    Key features and details

    • Rabbit polyclonal to SLC6A8
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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    Overview

    • Product name

      Anti-SLC6A8 antibody
      See all SLC6A8 primary antibodies
    • Description

      Rabbit polyclonal to SLC6A8
    • Host species

      Rabbit
    • Tested Applications & Species

      Application Species
      WB
      Human
      See all applications and species data
    • Immunogen

      Synthetic peptide corresponding to the C-terminal region of Human SLC6A8.

    • Positive control

      • HUVEC cell lysate

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    • Storage buffer

      pH: 7.40
      Preservative: 0.02% Sodium azide
      Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

      PBS is without Mg2+ and Ca2+.
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Metabolism
      • Plasma Membrane
      • Channels

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab137198 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    WB
    Human
    All applications
    Mouse
    Rat
    Application Abreviews Notes
    WB
    1/500 - 1/1000. Predicted molecular weight: 70 kDa.
    Notes
    WB
    1/500 - 1/1000. Predicted molecular weight: 70 kDa.

    Target

    • Function

      Required for the uptake of creatine in muscles and brain.
    • Tissue specificity

      Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
    • Involvement in disease

      Cerebral creatine deficiency syndrome 1
    • Sequence similarities

      Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession P48029 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 6535 Human
      • Entrez Gene: 102857 Mouse
      • Entrez Gene: 50690 Rat
      • Omim: 300036 Human
      • SwissProt: P48029 Human
      • SwissProt: Q8VBW1 Mouse
      • SwissProt: P28570 Rat
      • Unigene: 540696 Human
      • Unigene: 274553 Mouse
      • Unigene: 10336 Rat
      see all
    • Alternative names

      • SLC6A 8 antibody
      • SLC6A8 antibody
      • Creatine transporter 1 antibody
      • Creatine transporter SLC6A8 antibody
      • CRT antibody
      • CRTR antibody
      • CT 1 antibody
      • CT1 antibody
      • MGC87396 antibody
      • SC6A8_HUMAN antibody
      • Slc6a8 antibody
      • Sodium and chloride-dependent creatine transporter 1 antibody
      • Sodium- and chloride-dependent creatine transporter 1 antibody
      • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
      • Solute carrier family 6 member 8 antibody
      see all

    Images

    • Western blot - Anti-SLC6A8 antibody (ab137198)
      Western blot - Anti-SLC6A8 antibody (ab137198)
      Anti-SLC6A8 antibody (ab137198) at 1/500 dilution + HUVEC cell lysate at 30 µg

      Predicted band size: 70 kDa

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab137198? Please let us know so that we can cite the reference in this datasheet.

    ab137198 has not yet been referenced specifically in any publications.

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