Overview

  • Product name

  • Description

    Rabbit polyclonal to SLC6A8
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human SLC6A8 aa 582-635.
    Database link: P48029

  • Positive control

    • WB: SH-SY5Y whole cell lysate; Mouse heart lysate. ICC/IF: PC-3 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity greater than 95%.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab237023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/5000. Predicted molecular weight: 70 kDa.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Required for the uptake of creatine in muscles and brain.
  • Tissue specificity

    Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
  • Involvement in disease

    Cerebral creatine deficiency syndrome 1
  • Sequence similarities

    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • SLC6A 8 antibody
    • SLC6A8 antibody
    • Creatine transporter 1 antibody
    • Creatine transporter SLC6A8 antibody
    • CRT antibody
    • CRTR antibody
    • CT 1 antibody
    • CT1 antibody
    • MGC87396 antibody
    • SC6A8_HUMAN antibody
    • Slc6a8 antibody
    • Sodium and chloride-dependent creatine transporter 1 antibody
    • Sodium- and chloride-dependent creatine transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
    • Solute carrier family 6 member 8 antibody
    see all

Images

  • All lanes : Anti-SLC6A8 antibody (ab237023) at 1/500 dilution

    Lane 1 : SH-SY5Y (human neuroblastoma cell line from bone marrow) whole cell lysate
    Lane 2 : Mouse heart lysate

    Secondary
    All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution

    Predicted band size: 70 kDa

  • PC-3 (human prostate adenocarcinoma cell line) cells stained for SLC6A8 (green) using ab237023 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

References

ab237023 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab237023.
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