Key features and details
- Rabbit polyclonal to SLC6A8
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SLC6A8 antibody
See all SLC6A8 primary antibodies
DescriptionRabbit polyclonal to SLC6A8
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog
- IHC-P: Human muscle tissue. WB: MDA-MB-435s and THP-1 cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab62196 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 70, 80, 58 kDa (predicted molecular weight: 71 kDa).
Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
|IHC-P||Use a concentration of 4 - 8 µg/ml.|
FunctionRequired for the uptake of creatine in muscles and brain.
Tissue specificityPredominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
Involvement in diseaseCerebral creatine deficiency syndrome 1
Sequence similaritiesBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
- Information by UniProt
- SLC6A 8 antibody
- SLC6A8 antibody
- Creatine transporter 1 antibody
All lanes : Anti-SLC6A8 antibody (ab62196) at 1 µg/ml
Lane 1 : MDA-MB-435s cell lysate
Lane 2 : THP-1 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 71 kDa
Additional bands at: 58 kDa (possible isoform), 70 kDa (possible isoform), 80 kDa (possible isoform)
Western blot analysis labeling SLC6A8 with ab62196.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling SLC6A8 with ab62196 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.
ab62196 has been referenced in 1 publication.
- Heinbockel L et al. Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 13:2255-2259 (2018). PubMed: 30100715