Overview

  • Product name

    Anti-SLC7A9 antibody - C-terminal
    See all SLC7A9 primary antibodies
  • Description

    Rabbit polyclonal to SLC7A9 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Recombinant fragment within Human SLC7A9 (C terminal). The exact sequence is proprietary.
    Database link: P82251

  • Positive control

    • WB: Human kidney tissue extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab229602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.

Target

  • Relevance

    SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.
  • Cellular localization

    Membrane; multi pass membrane protein (probable)
  • Database links

  • Alternative names

    • B(0+) type amino acid transporter 1 antibody
    • BAT1 antibody
    • CSNU3 antibody
    • Glycoprotein associated amino acid transporter b0+AT1 antibody
    • Solute carrier family 7 (cationic amino acid transporter y+ system) member 9 antibody
    see all

Images

  • Anti-SLC7A9 antibody - C-terminal (ab229602) at 1/500 dilution + human kidney tissue extract at 30 µg

    Predicted band size: 53 kDa



    10% SDS-PAGE gel.

References

ab229602 has not yet been referenced specifically in any publications.

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