Overview

  • Product name

    Anti-SLCO1B3/OATP1B3 antibody
    See all SLCO1B3/OATP1B3 primary antibodies
  • Description

    Rabbit polyclonal to SLCO1B3/OATP1B3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human SLCO1B3/OATP1B3 aa 639-668 (C terminal) conjugated to keyhole limpet haemocyanin.
    Database link: NP_062818.1

  • Positive control

    • NCI-H460 cell line lysates.
  • General notes

     This product was previously labelled as SLCO1B3

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab139120 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab139120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.

Target

  • Function

    Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver.
  • Tissue specificity

    Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
  • Involvement in disease

    Hyperbilirubinemia, Rotor type
  • Sequence similarities

    Belongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Basolateral cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • HBLRR antibody
    • Liver-specific organic anion transporter 2 antibody
    • LST-2 antibody
    • LST-3TM13 antibody
    • LST3 antibody
    • OATP-8 antibody
    • OATP1B3 antibody
    • Organic anion transporter 8 antibody
    • Organic anion-transporting polypeptide 8 antibody
    • SLC21A8 antibody
    • SLCO1B3 antibody
    • SO1B3_HUMAN antibody
    • Solute carrier family 21 member 8 antibody
    • Solute carrier organic anion transporter family member 1B3 antibody
    see all

Images

  • Anti-SLCO1B3/OATP1B3 antibody (ab139120) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Developed using the ECL technique.

    Predicted band size: 77 kDa

References

ab139120 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139120.
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