Key features and details
- Mouse monoclonal [CL3770] to SLCO1B3/OATP1B3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-SLCO1B3/OATP1B3 antibody [CL3770]
See all SLCO1B3/OATP1B3 primary antibodies
DescriptionMouse monoclonal [CL3770] to SLCO1B3/OATP1B3
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
- IHC-P: Human liver tissue.
This product was previously labelled as SLCO1B3
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityProtein A purified
Purification notesPurified from TCS.
Our Abpromise guarantee covers the use of ab242368 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver.
Tissue specificityHighly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
Involvement in diseaseHyperbilirubinemia, Rotor type
Sequence similaritiesBelongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.
Cellular localizationBasolateral cell membrane.
- Information by UniProt
- HBLRR antibody
- Liver-specific organic anion transporter 2 antibody
- LST-2 antibody
Formalin-fixed, paraffin-embedded human liver tissue stained for SLCO1B3/OATP1B3 with ab242368 at a 1:200 dilution in immunohistochemical analysis.
Negative control - Formalin-fixed, paraffin-embedded human pancreas tissue stained for SLCO1B3/OATP1B3 with ab242368 at a 1:200 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab242368 has not yet been referenced specifically in any publications.