Overview

  • Product name

  • Description

    Rabbit polyclonal to SLCO1C1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 11-274 of Human SLCO1C1 (UniProt: Q9NYB5).

  • Positive control

    • PC3 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab154231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 79 kDa.

Target

  • Function

    Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain.
  • Tissue specificity

    Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
  • Sequence similarities

    Belongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • Cellular localization

    Cell membrane. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells. Localized to the apical membrane and basal surfaces of choroid plexus.
  • Information by UniProt
  • Database links

  • Alternative names

    • OAT-RP-5 antibody
    • OATP-14 antibody
    • OATP-F antibody
    • OATP1 antibody
    • OATP1C1 antibody
    • OATPRP5 antibody
    • Organic anion transporter F antibody
    • Organic anion transporter polypeptide-related protein 5 antibody
    • organic anion transporting polypeptide 14 antibody
    • Organic anion-transporting polypeptide 14 antibody
    • SLC21A14 antibody
    • Slco1c1 antibody
    • SO1C1_HUMAN antibody
    • solute carrier family 21 (organic anion transporter), member 14 antibody
    • Solute carrier family 21 member 14 antibody
    • Solute carrier organic anion transporter family member 1C1 antibody
    • solute carrier organic anion transporter family, member 1C1 antibody
    • Thyroxine transporter antibody
    see all

Images

  • Anti-SLCO1C1 antibody (ab154231) at 1/1000 dilution + PC3 whole cell
    lysate at 30 µg

    Predicted band size: 79 kDa



    7.5% SDS PAGE

References

ab154231 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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