Overview

  • Product name

  • Description

    Rabbit polyclonal to SLCO1C1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SLCO1C1 aa 97-348.
    Database link: Q9NYB5

  • Positive control

    • IHC-P: Human testis tissue. ICC/IF: HepG2 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.03% Proclin
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab234729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain.
  • Tissue specificity

    Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
  • Sequence similarities

    Belongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • Cellular localization

    Cell membrane. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells. Localized to the apical membrane and basal surfaces of choroid plexus.
  • Information by UniProt
  • Database links

  • Alternative names

    • OAT-RP-5 antibody
    • OATP-14 antibody
    • OATP-F antibody
    • OATP1 antibody
    • OATP1C1 antibody
    • OATPRP5 antibody
    • Organic anion transporter F antibody
    • Organic anion transporter polypeptide-related protein 5 antibody
    • organic anion transporting polypeptide 14 antibody
    • Organic anion-transporting polypeptide 14 antibody
    • SLC21A14 antibody
    • Slco1c1 antibody
    • SO1C1_HUMAN antibody
    • solute carrier family 21 (organic anion transporter), member 14 antibody
    • Solute carrier family 21 member 14 antibody
    • Solute carrier organic anion transporter family member 1C1 antibody
    • solute carrier organic anion transporter family, member 1C1 antibody
    • Thyroxine transporter antibody
    see all

Images

  • Paraffin-embedded human testis tissue stained for SLCO1C1 with ab234729 at 1/100 dilution in immunohistochemical analysis.

  • HepG2 (human liver hepatocellular carcinoma cell line) cells stained for SLCO1C1 using ab234729 at a dilution of 1/100 in ICC/IF. Secondary antibody is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).

References

ab234729 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab234729.
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