Recombinant Anti-SLCO2B1/OATP2B1 antibody [EPR22212-37] (ab245246)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR22212-37] to SLCO2B1/OATP2B1
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
-
Product name
Anti-SLCO2B1/OATP2B1 antibody [EPR22212-37]
See all SLCO2B1/OATP2B1 primary antibodies -
Description
Rabbit monoclonal [EPR22212-37] to SLCO2B1/OATP2B1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
Positive control
- WB: Human placenta and liver lysates.
-
General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR22212-37 -
Isotype
IgG -
Research areas
Associated products
-
Alternative Versions
-
Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab245246 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 77 kDa).
|
Notes |
---|
WB
1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 77 kDa). |
Target
-
Relevance
SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins. -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 11309 Human
- Omim: 604988 Human
- SwissProt: O94956 Human
-
Alternative names
- Moat 1 antibody
- Moat1 antibody
- Multispecific organic anion transporter 1 antibody
see all
Images
-
All lanes : Anti-SLCO2B1/OATP2B1 antibody [EPR22212-37] (ab245246) at 1/1000 dilution
Lane 1 : Human placenta tissue lysate
Lane 2 : Human liver tissue lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : VeriBlot for IP Detection Reagent (HRP) (ab131366) at 1/1000 dilution
Predicted band size: 77 kDa
Observed band size: 85 kDa why is the actual band size different from the predicted?Exposure time : Lane 1: 3 seconds; Lane 2: 37 seconds.
Blocking/Dilution buffer: 5% NFDM/TBST.
The expression profile/ molecular weight observed is consistent with what has been described in the literature (PMID:11159893; PMID:16357150; PMID:17020956).
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
Certificate of Compliance
References (0)
ab245246 has not yet been referenced specifically in any publications.