Overview

  • Product name
    Anti-Slit1 antibody [EP5796(N)]
    See all Slit1 primary antibodies
  • Description
    Rabbit monoclonal [EP5796(N)] to Slit1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Slit1 aa 50-150. The exact sequence is proprietary.
    Database link: O75093

  • Positive control
    • Human fetal brain and forebrain lysates; SH-SY5Y cell lysate.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab183704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 200 kDa (predicted molecular weight: 168 kDa).

Target

  • Function
    Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
  • Tissue specificity
    Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
  • Sequence similarities
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 9 EGF-like domains.
    Contains 1 laminin G-like domain.
    Contains 20 LRR (leucine-rich) repeats.
    Contains 4 LRRCT domains.
    Contains 4 LRRNT domains.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0813 antibody
    • MEGF 4 antibody
    • MEGF4 antibody
    • MGC164811 antibody
    • Multiple EGF-like domains protein 4 antibody
    • Multiple epidermal growth factor like domains 4 antibody
    • Multiple epidermal growth factor-like domains protein 4 antibody
    • OTTHUMP00000059392 antibody
    • SLIL 1 antibody
    • SLIL1 antibody
    • Slit 1 antibody
    • SLIT 3 antibody
    • Slit homolog 1 antibody
    • Slit homolog 1 protein antibody
    • Slit-1 antibody
    • Slit1 antibody
    • SLIT1_HUMAN antibody
    • SLIT3 antibody
    see all

Images

  • Anti-Slit1 antibody [EP5796(N)] (ab183704) at 1/1000 dilution + SH-SY5Y cell lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

    Predicted band size: 168 kDa

  • All lanes : Anti-Slit1 antibody [EP5796(N)] (ab183704) at 1/1000 dilution

    Lane 1 : Human fetal brain lysate
    Lane 2 : Human fetal forebrain lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

    Predicted band size: 168 kDa

References

ab183704 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab183704.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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