Overview

  • Product name

    Anti-Slit1 antibody [EP5797(2)]
    See all Slit1 primary antibodies
  • Description

    Rabbit monoclonal [EP5797(2)] to Slit1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human Slit1 (UniProt: O75093).

  • Positive control

    • Human fetal brain lysate.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab151724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 168 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function

      Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
    • Tissue specificity

      Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
    • Sequence similarities

      Contains 1 CTCK (C-terminal cystine knot-like) domain.
      Contains 9 EGF-like domains.
      Contains 1 laminin G-like domain.
      Contains 20 LRR (leucine-rich) repeats.
      Contains 4 LRRCT domains.
      Contains 4 LRRNT domains.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • KIAA0813 antibody
      • MEGF 4 antibody
      • MEGF4 antibody
      • MGC164811 antibody
      • Multiple EGF-like domains protein 4 antibody
      • Multiple epidermal growth factor like domains 4 antibody
      • Multiple epidermal growth factor-like domains protein 4 antibody
      • OTTHUMP00000059392 antibody
      • SLIL 1 antibody
      • SLIL1 antibody
      • Slit 1 antibody
      • SLIT 3 antibody
      • Slit homolog 1 antibody
      • Slit homolog 1 protein antibody
      • Slit-1 antibody
      • Slit1 antibody
      • SLIT1_HUMAN antibody
      • SLIT3 antibody
      see all

    Images

    • Anti-Slit1 antibody [EP5797(2)] (ab151724) at 1/1000 dilution + Human fetal brain lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 168 kDa

    References

    ab151724 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151724.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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