Anti-Slit3 antibody (ab198726)
Key features and details
- Rabbit polyclonal to Slit3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Slit3 antibody
See all Slit3 primary antibodies -
Description
Rabbit polyclonal to Slit3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human Slit3 (internal sequence). NP_003053.
Database link: O75094 -
Positive control
- Human liver cancer tissue and Human esophagus cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab198726 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/25 - 1/100.
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Notes |
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IHC-P
1/25 - 1/100. |
Target
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Function
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. -
Tissue specificity
Predominantly expressed in thyroid. -
Sequence similarities
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 9 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 20 LRR (leucine-rich) repeats.
Contains 4 LRRCT domains.
Contains 4 LRRNT domains. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6586 Human
- Omim: 603745 Human
- SwissProt: O75094 Human
- Unigene: 604116 Human
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Alternative names
- FLJ10764 antibody
- KIAA0814 antibody
- MEGF 5 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab198726 has been referenced in 2 publications.
- Zhong W et al. Gingival crevicular fluid levels of SLIT3 are increased in periodontal disease. Oral Dis 26:182-192 (2020). PubMed: 31696592
- Xu R et al. Targeting skeletal endothelium to ameliorate bone loss. Nat Med 24:823-833 (2018). PubMed: 29785024