Overview

  • Product name

  • Description

    Rabbit polyclonal to SLITRK5
  • Host species

    Rabbit
  • Specificity

    ab67309 is predicted to have no cross-reactivity to other SLITRK proteins.
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 14 amino acid synthetic peptide from near the center of human SLITRK5.

  • Positive control

    • 3T3 cell lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 160 kDa (predicted molecular weight: 107 kDa).
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Relevance

    SLIT and NTRK-like family 5 (SLITRK5) is a member a protein family consisting of six homologous transmembrane proteins (SLITRK1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of SLITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other SLITRK protein except SLITRK1, overexpression of SLITRK5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
  • Cellular localization

    Membrane; Single-pass type I membrane protein.
  • Database links

  • Alternative names

    • bA364G4.2 antibody
    • KIAA0918 antibody
    • Leucine rich repeat containing 11 antibody
    • Leucine rich repeat containing protein 11 antibody
    • LRRC 11 antibody
    • LRRC11 antibody
    • SLIT and NTRK like family member 5 antibody
    • SLIT and NTRK like protein 5 antibody
    • Slit and trk like gene 5 antibody
    • SLITRK 5 antibody
    see all

Images

  • All lanes : Anti-SLITRK5 antibody (ab67309) at 1 µg/ml

    Lane 1 : 3T3 cell lysate with no blocking peptide
    Lane 2 : 3T3 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 107 kDa
    Observed band size: 160 kDa
    why is the actual band size different from the predicted?

  • Immunofluorescence of SLITRK5 in Human Brain cells using ab67309 at 5 µg/ml.

References

This product has been referenced in:

  • Kogan-Sakin I  et al. Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells. Cell Death Differ : (2010). Read more (PubMed: 20689556) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab67309.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up