Key features and details
- Mouse monoclonal [7G8C10] to SLM-1 - C-terminal
- Suitable for: Flow Cyt, IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG1
Product nameAnti-SLM-1 antibody [7G8C10] - C-terminal
DescriptionMouse monoclonal [7G8C10] to SLM-1 - C-terminal
Tested applicationsSuitable for: Flow Cyt, IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Recombinant fragment corresponding to Human SLM-1 aa 160-349.
V PDYNDEIRQE QLRELSYLNG SEDSGRGRGI RGRGIRIAPT APSRGRGGAI PPPPPPGRGV LTPRGSTVTR GALPVPPVAR GVPTPRARGA PTVPGYRAPP PPAHEAYEEY GYDDGYGGEY DDQTYETYDN SYATQTQSVP EYYDYGHGVS EDAYDSYAPE EWATTRSSLK APPQRSARGG YREHPYGRY
Database link: Q5VWX1
- Human SLM-1 (AA: 160-349) recombinant protein. K562, HEK293, NTERA-2, HeLa, HepG2, Jurkat, A431 and NIH/3T3 cell lysate. K562 cells. Human cervical cancer tissues. Human colon cancer tissues.
Previously labelled as KHDRBS2.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein G purified
Purification notesPurified from tissue culture supernatant.
Our Abpromise guarantee covers the use of ab201982 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||1/200 - 1/400.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|IHC-P||1/200 - 1/1000.|
|WB||1/500 - 1/2000. Predicted molecular weight: 39 kDa.|
FunctionRNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Tissue specificityHighly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
Sequence similaritiesBelongs to the KHDRBS family.
Contains 1 KH domain.
Tyrosine phosphorylated by FYN, PTK6 and SRC. Tyrosine phosphorylated by SRC during mitosis.
- Information by UniProt
- KH domain containing, RNA binding, signal transduction associated protein 2 antibody
- 6330586C16Rik antibody
- bA535F17.1 antibody
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue labeling SLM-1 with ab201982 at 1/200 dilution with DAB staining.
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue labeling SLM-1 with ab201982 at 1/200 dilution with DAB staining.
Flow cytometric analysis of K562 cells using ab201982 at 1/200 dilution (green) and negative control (red).
All lanes : Anti-SLM-1 antibody [7G8C10] - C-terminal (ab201982) at 1/500 dilution
Lane 1 : K562 cell lysate
Lane 2 : HEK293 cell lysate
Lane 3 : NTERA-2 cell lysate
Lane 4 : HeLa cell lysate
Lane 5 : HepG2 cell lysate
Lane 6 : Jurkat cell lysate
Lane 7 : A431 cell lysate
Lane 8 : NIH/3T3 cell lysate
Predicted band size: 39 kDa
Anti-SLM-1 antibody [7G8C10] - C-terminal (ab201982) at 1/500 dilution + Human SLM-1 (AA: 160-349) recombinant protein
Predicted band size: 39 kDa
ab201982 has not yet been referenced specifically in any publications.