Overview

  • Product name

    SM 7368, NF-kappaB inhibitor
  • Description

    Selective NF-κB inhibitor
  • Biological description

    Selective NF-κB inhibitor. Inhibits TNF-α induced MMP-9 expression. Decreases MMP-9 expression in AMPKα knockout cells. Putative antimetastatic agent.
  • Purity

    > 99%
  • CAS Number

    380623-76-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Samuel T  et al. Variable NF-?B pathway responses in colon cancer cells treated with chemotherapeutic drugs. BMC Cancer 14:599 (2014). Read more (PubMed: 25134433) »
  • Morizane Y  et al. AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts. J Biol Chem 286:16030-8 (2011). Read more (PubMed: 21402702) »
  • Wang J  et al. TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. J Biol Chem 286:39738-49 (2011). Read more (PubMed: 21949132) »

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