Overview

  • Product name

    SM64, beta1 adrenoceptor antagonist
  • Description

    Highly selective β1 adrenoceptor antagonist and partial agonist
  • Biological description

    Highly selective β1 adrenoceptor antagonist (log KD = -7.5 for β1 and incomplete binding inhibition for β2). Exhibits β1-partial agonist activity (log EC50 = -8; 34% isoprenalinie maximum). Active in vitro and in vivo.
  • Purity

    > 97%
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mistry SN  et al. Synthesis and in vitro and in vivo characterization of highly ß1-selective ß-adrenoceptor partial agonists. J Med Chem 56:3852-65 (2013). Read more (PubMed: 23614528) »

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