Key features and details
- Highly selective β1 adrenoceptor antagonist and partial agonist
- CAS Number:
- Purity: > 97%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameSM64, beta1 adrenoceptor antagonist
DescriptionHighly selective β1 adrenoceptor antagonist and partial agonist
Highly selective β1 adrenoceptor antagonist (log KD = -7.5 for β1 and incomplete binding inhibition for β2). Exhibits β1-partial agonist activity (log EC50 = -8; 34% isoprenalinie maximum). Active in vitro and in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144659 has not yet been referenced specifically in any publications.