Recombinant
RabMAb

Recombinant Anti-Smad3 (phospho S423 + S425) antibody [EP823Y] (ab52903)

Publishing research using ab52903? Please let us know so that we can cite the reference in this datasheet.

ab52903 has been referenced in 205 publications.

  • Zhang J  et al. Cyclic Adenosine Monophosphate Promotes Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via Suppression of Transforming Growth Factor Beta 1 Signaling. J Endod 45:150-155 (2019). PubMed: 30711170
  • Nixon AML  et al. A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations. Sci Rep 9:842 (2019). PubMed: 30696911
  • Wang Y  et al. Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction. Biochim Biophys Acta Mol Basis Dis N/A:N/A (2019). PubMed: 30639224
  • Held A  et al. Circuit Dysfunction in SOD1-ALS Model First Detected in Sensory Feedback Prior to Motor Neuron Degeneration Is Alleviated by BMP Signaling. J Neurosci 39:2347-2364 (2019). PubMed: 30659087
  • Wang B  et al. POH1 contributes to hyperactivation of TGF-ß signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-ß receptors and caveolin-1. EBioMedicine 41:320-332 (2019). PubMed: 30745168
  • Naciri I  et al. Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors. Nucleic Acids Res 47:3407-3421 (2019). PubMed: 30753595
  • Hu L  et al. Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFß receptor I-mediated signaling. Exp Eye Res 182:44-56 (2019). PubMed: 30914160
  • Baxter E  et al. Molecular basis of distinct oestrogen responses in endometrial and breast cancer. Endocr Relat Cancer 26:31-46 (2019). PubMed: 30121621
  • Nakayama Y  et al. C/EBPß and YY1 bind and interact with Smad3 to modulate lipopolysaccharide-induced amelotin gene transcription in mouse gingival epithelial cells. FEBS Open Bio 9:276-290 (2019). PubMed: 30761253
  • Ulmasov B  et al. An Inhibitor of Arginine-Glycine-Aspartate-Binding Integrins Reverses Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. Hepatol Commun 3:246-261 (2019). PubMed: 30766962
  • Granados-Aparici S  et al. SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles. Sci Rep 9:6513 (2019). PubMed: 31015579
  • Fang L  et al. MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-ß pathway in NSCLC. Oncogene 38:896-912 (2019). PubMed: 30181549
  • MacFarlane EG  et al. Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome. J Clin Invest 129:659-675 (2019). PubMed: 30614814
  • Maksoud E  et al. A Neuron-Glial Trans-Signaling Cascade Mediates LRRK2-Induced Neurodegeneration. Cell Rep 26:1774-1786.e4 (2019). PubMed: 30759389
  • Xu N  et al. Stent-Jailing Technique Reduces Aneurysm Recurrence More Than Stent-Jack Technique by Causing Less Mechanical Forces and Angiogenesis and Inhibiting TGF-ß/Smad2,3,4 Signaling Pathway in Intracranial Aneurysm Patients. Front Physiol 9:1862 (2018). PubMed: 30670979
  • Qiu C  et al. Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease. Nat Med 24:1721-1731 (2018). PubMed: 30275566
  • Li L  et al. Inhibition of Ep3 attenuates migration and promotes apoptosis of non-small cell lung cancer cells via suppression of TGF-ß/Smad signaling. Oncol Lett 16:5645-5654 (2018). PubMed: 30344720
  • Flora P  et al. Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3' UTRs. Cell Rep 25:3828-3843.e9 (2018). PubMed: 30590052
  • McCarthy A  et al. Tip60 complex promotes expression of a differentiation factor to regulate germline differentiation in female Drosophila. Mol Biol Cell 29:2933-2945 (2018). PubMed: 30230973
  • Qin Z  et al. Actin cytoskeleton assembly regulates collagen production via TGF-ß type II receptor in human skin fibroblasts. J Cell Mol Med 22:4085-4096 (2018). PubMed: 29888864
  • Futakuchi A  et al. YAP/TAZ Are Essential for TGF-ß2-Mediated Conjunctival Fibrosis. Invest Ophthalmol Vis Sci 59:3069-3078 (2018). PubMed: 30025139
  • Cai X  et al. Silence of IGFBP7 suppresses apoptosis and epithelial mesenchymal transformation of high glucose induced-podocytes. Exp Ther Med 16:1095-1102 (2018). PubMed: 30112052
  • Tsogbadrakh B  et al. HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral obstruction model. PLoS One 13:e0201692 (2018). PubMed: 30161162
  • Strauss FJ  et al. Acid bone lysate activates TGFß signalling in human oral fibroblasts. Sci Rep 8:16065 (2018). PubMed: 30375456
  • Kofler N  et al. The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling. J Biol Chem 293:4805-4817 (2018). PubMed: 29425100
  • Bird TG  et al. TGFß inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Sci Transl Med 10:N/A (2018). PubMed: 30111642
  • Abraham DM  et al. The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. J Clin Invest 128:4843-4855 (2018). PubMed: 30153110
  • Tyagi AM  et al. The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression. Immunity 49:1116-1131.e7 (2018). PubMed: 30446387
  • Jin Q  et al. Neonatal Systemic AAV-Mediated Gene Delivery of GDF11 Inhibits Skeletal Muscle Growth. Mol Ther 26:1109-1117 (2018). PubMed: 29503194
  • Park JW  et al. AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development. Mol Cancer Res 16:1287-1298 (2018). PubMed: 29724814
  • Chen H  et al. RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD. Cell Death Dis 9:878 (2018). PubMed: 30158627
  • Schoenmaker T  et al. The effect of Activin-A on periodontal ligament fibroblasts-mediated osteoclast formation in healthy donors and in patients with fibrodysplasia ossificans progressiva. J Cell Physiol N/A:N/A (2018). PubMed: 30417373
  • Jia Q  et al. Genistein attenuates renal fibrosis in streptozotocin-induced diabetic rats. Mol Med Rep N/A:N/A (2018). PubMed: 30431100
  • Ling L  et al. Carvedilol Ameliorates Intrahepatic Angiogenesis, Sinusoidal Remodeling and Portal Pressure in Cirrhotic Rats. Med Sci Monit 24:8290-8297 (2018). PubMed: 30448852
  • Luu AK  et al. An evaluation of TAZ and YAP crosstalk with TGFß signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression. BMC Vet Res 14:365 (2018). PubMed: 30477496
  • Lim BJ  et al. Selective deletion of hepatocyte platelet-derived growth factor receptor a and development of liver fibrosis in mice. Cell Commun Signal 16:93 (2018). PubMed: 30509307
  • Zhang S  et al. Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition. Front Physiol 9:1650 (2018). PubMed: 30524310
  • Liu W  et al. Transforming growth factor-ß1 up-regulates connexin43 expression in osteocytes via canonical Smad-dependent signaling pathway. Biosci Rep 38:N/A (2018). PubMed: 30482881
  • Muppala S  et al. YAP and TAZ are distinct effectors of corneal myofibroblast transformation. Exp Eye Res 180:102-109 (2018). PubMed: 30578787
  • Gaitantzi H  et al. Ethanol sensitizes hepatocytes for TGF-ß-triggered apoptosis. Cell Death Dis 9:51 (2018). PubMed: 29352207
  • Le V  et al. Drosophila models of FOP provide mechanistic insight. Bone 109:192-200 (2018). WB, IHC ; Drosophila melanogaster . PubMed: 29128351
  • Syed S  et al. High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children. PLoS Negl Trop Dis 12:e0006224 (2018). PubMed: 29415065
  • Li J  et al. MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Mol Ther Nucleic Acids 10:426-437 (2018). PubMed: 29499953
  • Zhang X  et al. ING5 is a Potential Target for Osteosarcoma Therapy. Technol Cancer Res Treat 17:1533033818762680 (2018). PubMed: 29528777
  • Wu Y  et al. Autocrine transforming growth factor-ß/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states. Biochimie 148:87-98 (2018). PubMed: 29544731
  • Criem N & Zwijsen A The epicardium obscures interpretations on endothelial-to-mesenchymal transition in the mouse atrioventricular canal explant assay. Sci Rep 8:4722 (2018). PubMed: 29549339
  • Ament SA  et al. Transcriptional regulatory networks underlying gene expression changes in Huntington's disease. Mol Syst Biol 14:e7435 (2018). PubMed: 29581148
  • Zhang P  et al. Salidroside Inhibits Myogenesis by Modulating p-Smad3-Induced Myf5 Transcription. Front Pharmacol 9:209 (2018). PubMed: 29593538
  • Flora P  et al. Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila. Dev Biol 434:84-95 (2018). WB . PubMed: 29198563
  • Wang X & Page-McCaw A Wnt6 maintains anterior escort cells as an integral component of the germline stem cell niche. Development 145:N/A (2018). PubMed: 29361569
  • Upadhyay M  et al. A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila. PLoS Genet 14:e1007154 (2018). PubMed: 29370168
  • Wang X  et al. Therapeutic effects of conditioned medium from bone marrow-derived mesenchymal stem cells on epithelial-mesenchymal transition in A549 cells. Int J Mol Med 41:659-668 (2018). ICC/IF . PubMed: 29207055
  • Cheng Z  et al. The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway. Exp Mol Med 50:e447 (2018). WB . PubMed: 29504607
  • Xu R  et al. Self-restrained regulation of stem cell niche activity by niche components in the Drosophila testis. Dev Biol 439:42-51 (2018). PubMed: 29679558
  • Dave JM  et al. Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain. Dev Cell 44:665-678.e6 (2018). PubMed: 29456135
  • Xu Q  et al. Comparative analysis of the two extremes of FLNB-mutated autosomal dominant disease spectrum: from clinical phenotypes to cellular and molecular findings. Am J Transl Res 10:1400-1412 (2018). PubMed: 29887954
  • Sheng J  et al. M2 macrophage-mediated interleukin-4 signalling induces myofibroblast phenotype during the progression of benign prostatic hyperplasia. Cell Death Dis 9:755 (2018). PubMed: 29988032
  • Zhang Y  et al. TGF-ß3 Promotes MUC5AC Hyper-Expression by Modulating Autophagy Pathway in Airway Epithelium. EBioMedicine 33:242-252 (2018). PubMed: 29997053
  • Wei G  et al. LY2109761 reduces TGF-ß1-induced collagen production and contraction in hypertrophic scar fibroblasts. Arch Dermatol Res 310:615-623 (2018). PubMed: 30046895
  • Chen K  et al. Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF-ß1/Smad3 signaling pathway. Mol Med Rep 17:7652-7660 (2018). PubMed: 29620209
  • Chen MT  et al. Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFß/SMAD signaling pathway. Oncol Lett 15:8582-8588 (2018). PubMed: 29805593
  • Apitz H & Salecker I Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila. Nat Commun 9:2295 (2018). PubMed: 29895891
  • Liao EH  et al. Kinesin Khc-73/KIF13B modulates retrograde BMP signaling by influencing endosomal dynamics at the Drosophila neuromuscular junction. PLoS Genet 14:e1007184 (2018). IHC ; Drosophila melanogaster . PubMed: 29373576
  • de Vries TJ  et al. Periodontal ligament fibroblasts as a cell model to study osteogenesis and osteoclastogenesis in fibrodysplasia ossificans progressiva. Bone 109:168-177 (2018). WB . PubMed: 28705683
  • Park S  et al. Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation. J Cancer Prev 23:1-9 (2018). Human . PubMed: 29629343
  • Armstrong AR & Drummond-Barbosa D Insulin signaling acts in adult adipocytes via GSK-3ß and independently of FOXO to control Drosophila female germline stem cell numbers. Dev Biol N/A:N/A (2018). IHC . PubMed: 29729259
  • Zhang Y  et al. Matrine suppresses cardiac fibrosis by inhibiting the TGF-ß/Smad pathway in experimental diabetic cardiomyopathy. Mol Med Rep 17:1775-1781 (2018). PubMed: 29138820
  • Du D  et al. Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition. EMBO Rep 19:135-155 (2018). PubMed: 29233829
  • Song Q  et al. JAK/STAT3 and Smad3 activities are required for the wound healing properties of Periplaneta americana extracts. Int J Mol Med 40:465-473 (2017). WB, IHC-P, ICC/IF . PubMed: 28656220
  • Cammareri P  et al. TGFß pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis. Cell Death Differ 24:1681-1693 (2017). IHC ; Mouse . PubMed: 28622298
  • Cai J  et al. Simultaneous overactivation of Wnt/ß-catenin and TGFß signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC. Nat Commun 8:15870 (2017). PubMed: 28627514
  • Clements MP  et al. The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration. Neuron 96:98-114.e7 (2017). IHC-Fr . PubMed: 28957681
  • Pfefferli C & Jazwinska A The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin. Nat Commun 8:15151 (2017). IHC-Fr ; Zebrafish . PubMed: 28466843
  • Gao Y  et al. Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling. Reprod Biol Endocrinol 15:94 (2017). WB ; Mouse . PubMed: 29221447
  • Redgrave RE  et al. Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis. Stem Cell Reports 8:1287-1298 (2017). PubMed: 28494939
  • Sun Q  et al. ENMD-1068 inhibits liver fibrosis through attenuation of TGF-ß1/Smad2/3 signaling in mice. Sci Rep 7:5498 (2017). PubMed: 28710422
  • Zhang S  et al. Tumor-associated macrophages promote tumor metastasis via the TGF-ß/SOX9 axis in non-small cell lung cancer. Oncotarget 8:99801-99815 (2017). WB ; Human . PubMed: 29245941
  • Gong Y  et al. Low density lipoprotein - rosiglitazone - chitosan-calcium alginate/nanoparticles inhibition of human tenon's fibroblasts activation and proliferation. Oncotarget 8:105126-105136 (2017). PubMed: 29285239
  • Wotton KR  et al. Non-canonical dorsoventral patterning in the moth midgeClogmia albipunctata. Evodevo 8:20 (2017). PubMed: 29158889
  • Zeng X  et al. Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells. Oncotarget 8:72872-72885 (2017). PubMed: 29069832
  • Dufton NP  et al. Dynamic regulation of canonical TGFß signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Nat Commun 8:895 (2017). PubMed: 29026072
  • Murray IR  et al. av integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis. Nat Commun 8:1118 (2017). PubMed: 29061963
  • Morris AD  et al. Perineurial Glial Plasticity and the Role of TGF-ß in the Development of the Blood-Nerve Barrier. J Neurosci 37:4790-4807 (2017). PubMed: 28389474
  • Cao J  et al. CCAAT enhancer binding protein ß has a crucial role in regulating breast cancer cell growth via activating the TGF-ß-Smad3 signaling pathway. Exp Ther Med 14:1554-1560 (2017). PubMed: 28810620
  • Waters JP  et al. A 3D tri-culture system reveals that activin receptor-like kinase 5 and connective tissue growth factor drive human glomerulosclerosis. J Pathol 243:390-400 (2017). PubMed: 28815607
  • Galeone A  et al. Tissue-specific regulation of BMP signaling byDrosophila N-glycanase 1. Elife 6:N/A (2017). PubMed: 28826503
  • Al Khatib A  et al. Specific expression and function of the Six3optixinDrosophilaserially homologous organs. Biol Open 6:1155-1164 (2017). PubMed: 28642242
  • Wei Y  et al. Fibroblast-specific inhibition of TGF-ß1 signaling attenuates lung and tumor fibrosis. J Clin Invest 127:3675-3688 (2017). PubMed: 28872461
  • Sailland J  et al. Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells. Sci Rep 7:10506 (2017). PubMed: 28874823
  • Hu Q  et al. Baicalin and baicalein attenuate renal fibrosisin vitrovia inhibition of the TGF-ß1 signaling pathway. Exp Ther Med 14:3074-3080 (2017). PubMed: 28928802
  • Song W  et al. Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model. Proc Natl Acad Sci U S A N/A:N/A (2017). PubMed: 28739899
  • Feng Y  et al. Alpha-1-antitrypsin functions as a protective factor in preeclampsia through activating Smad2 and inhibitor of DNA binding 4. Oncotarget 8:113002-113012 (2017). PubMed: 29348884
  • Lai CM  et al. Hedgehog signaling establishes precursors for germline stem cell niches by regulating cell adhesion. J Cell Biol 216:1439-1453 (2017). IHC ; Drosophila melanogaster . PubMed: 28363970
  • Han Y  et al. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis. PLoS One 12:e0166014 (2017). IF ; Mouse . PubMed: 28135282
  • Yue L  et al. Efficacy of ALK5 inhibition in myelofibrosis. JCI Insight 2:e90932 (2017). WB ; Human . PubMed: 28405618
  • Lefebvre P  et al. Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARa-regulated dermatopontin. JCI Insight 2:N/A (2017). WB ; Mouse . PubMed: 28679947
  • Shen J  et al. DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. JCI Insight 2:N/A (2017). WB ; Mouse, Human . PubMed: 28614801
  • Xue R  et al. Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells. Stem Cell Res Ther 8:148 (2017). WB ; Human . PubMed: 28646917
  • Zeng Z  et al. Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression. Sci Rep 7:46146 (2017). WB . PubMed: 28393852
  • Breitkopf-Heinlein K  et al. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut 66:939-954 (2017). PubMed: 28336518
  • Soofi A  et al. The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. J Biol Chem 292:9051-9062 (2017). PubMed: 28424263
  • An M  et al. Different macrophages equally induce EMT in endometria of adenomyosis and normal. Reproduction 154:79-92 (2017). PubMed: 28495851
  • Abrial M  et al. TGF-ß Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Rep 20:973-983 (2017). PubMed: 28746880
  • Mah W  et al. Elevated CD26 Expression by Skin Fibroblasts Distinguishes a Profibrotic Phenotype Involved in Scar Formation Compared to Gingival Fibroblasts. Am J Pathol 187:1717-1735 (2017). PubMed: 28641076
  • An J  et al. Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR. Oncol Rep 38:3001-3010 (2017). PubMed: 29048681
  • Bajikar SS  et al. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell 43:418-435.e13 (2017). PubMed: 29161592
  • Epstein Shochet G  et al. First trimester human placenta prevents breast cancer cell attachment to the matrix: The role of extracellular matrix. Mol Carcinog 56:62-74 (2017). PubMed: 26859229
  • Wang Q  et al. Smad4-dependent suppressor pituitary homeobox 2 promotes PPP2R2A-mediated inhibition of Akt pathway in pancreatic cancer. Oncotarget 7:11208-22 (2016). PubMed: 26848620
  • Chen PY  et al. Smooth muscle FGF/TGFß cross talk regulates atherosclerosis progression. EMBO Mol Med 8:712-28 (2016). PubMed: 27189169
  • Sato N  et al. Metformin attenuates lung fibrosis development via NOX4 suppression. Respir Res 17:107 (2016). Human . PubMed: 27576730
  • Tappeiner C  et al. Inhibition of the TGFß Pathway Enhances Retinal Regeneration in Adult Zebrafish. PLoS One 11:e0167073 (2016). IHC-P ; Zebrafish . PubMed: 27880821
  • Klein JD  et al. c-Fos Repression by Piwi Regulates Drosophila Ovarian Germline Formation and Tissue Morphogenesis. PLoS Genet 12:e1006281 (2016). Drosophila melanogaster . PubMed: 27622269
  • Chen JL  et al. Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia. Cancer Res 76:5372-82 (2016). PubMed: 27328730
  • Soofi A  et al. The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice. Am J Physiol Gastrointest Liver Physiol 311:G587-G598 (2016). PubMed: 27514479
  • Neto M  et al. Increased avidity for Dpp/BMP2 maintains the proliferation of progenitors-like cells in the Drosophila eye. Dev Biol 418:98-107 (2016). IHC-P ; Drosophila melanogaster . PubMed: 27502436
  • Marro J  et al. Collagen XII Contributes to Epicardial and Connective Tissues in the Zebrafish Heart during Ontogenesis and Regeneration. PLoS One 11:e0165497 (2016). ICC/IF ; Zebrafish . PubMed: 27783651
  • Upadhyay M  et al. Transposon Dysregulation Modulates dWnt4 Signaling to Control Germline Stem Cell Differentiation in Drosophila. PLoS Genet 12:e1005918 (2016). PubMed: 27019121
  • Khalili H  et al. Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn's Disease and Ulcerative Colitis. Front Immunol 7:554 (2016). PubMed: 28003811
  • Kwan CW  et al. Functional evolution of a morphogenetic gradient. Elife 5:N/A (2016). PubMed: 28005004
  • Zhou Z  et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature 532:122-6 (2016). IHC . PubMed: 27027284
  • Omata M  et al. Hepatocyte Nuclear Factor-1ß Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells. PLoS One 11:e0154912 (2016). WB . PubMed: 27196561
  • Wu Q  et al. miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF. Sci Rep 6:30921 (2016). WB ; Mouse . PubMed: 27506999
  • Nakamichi R  et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun 7:12503 (2016). WB . PubMed: 27527664
  • Ren J  et al. Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and ß-catenin Signaling. Sci Rep 6:23968 (2016). WB, IF, IHC . PubMed: 27052477
  • Cao J  et al. Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration. Development 143:232-43 (2016). PubMed: 26657776
  • Hoare M  et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol 18:979-92 (2016). PubMed: 27525720
  • Mu X  et al. Epithelial Transforming Growth Factor-ß Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma. Gastroenterology 150:720-33 (2016). PubMed: 26627606
  • Chen S  et al. Transforming Growth Factor ß1 (TGF-ß1) Activates Hepcidin mRNA Expression in Hepatocytes. J Biol Chem 291:13160-74 (2016). PubMed: 27129231
  • Li H  et al. Ubx dynamically regulates Dpp signaling by repressing Dad expression during copper cell regeneration in the adult Drosophila midgut. Dev Biol 419:373-381 (2016). PubMed: 27570230
  • Ulmasov B  et al. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice. Cell Mol Gastroenterol Hepatol 2:499-518 (2016). PubMed: 28174730
  • Languino LR  et al. Exosome-mediated transfer from the tumor microenvironment increases TGFß signaling in squamous cell carcinoma. Am J Transl Res 8:2432-7 (2016). PubMed: 27347352
  • Hu ZY  et al. NDRG1 attenuates epithelial-mesenchymal transition of nasopharyngeal cancer cells via blocking Smad2 signaling. Biochim Biophys Acta 1852:1876-86 (2015). WB ; Human . PubMed: 26071641
  • Bashir M  et al. Activin-A signaling promotes epithelial-mesenchymal transition, invasion, and metastatic growth of breast cancer. NPJ Breast Cancer 1:15007 (2015). PubMed: 28721365
  • Lua I  et al. Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis. Am J Pathol 185:3258-73 (2015). ICC/IF ; Mouse . PubMed: 26598235
  • Ball RW  et al. BMP signaling and microtubule organization regulate synaptic strength. Neuroscience 291:155-66 (2015). IHC-P . PubMed: 25681521
  • Maquigussa E  et al. Calcitriol ameliorates renal damage in a pre-established proteinuria model. Mol Med Rep 12:1009-15 (2015). WB . PubMed: 25823676
  • Cui W  et al. Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFß signaling in macrophages. Cell Biosci 5:36 (2015). WB . PubMed: 26146544
  • Priyadarsini S  et al. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis 21:577-88 (2015). WB . PubMed: 26015770
  • Loiselle AE  et al. Development of antisense oligonucleotide (ASO) technology against Tgf-ß signaling to prevent scarring during flexor tendon repair. J Orthop Res 33:859-66 (2015). PubMed: 25761254
  • Chatterjee A  et al. Rapamycin-induced G1 cell cycle arrest employs both TGF-ß and Rb pathways. Cancer Lett 360:134-40 (2015). PubMed: 25659819
  • Hirota S  et al. Neuropilin 1 balances ß8 integrin-activated TGFß signaling to control sprouting angiogenesis in the brain. Development 142:4363-73 (2015). PubMed: 26586223
  • Budi EH  et al. The insulin response integrates increased TGF-ß signaling through Akt-induced enhancement of cell surface delivery of TGF-ß receptors. Sci Signal 8:ra96 (2015). WB ; Mouse . PubMed: 26420907
  • Nyström A  et al. Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms. EMBO Mol Med 7:1211-28 (2015). WB ; Human . PubMed: 26194911
  • Aspalter IM  et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun 6:7264 (2015). Mouse . PubMed: 26081042
  • Chen JL  et al. Development of novel activin-targeted therapeutics. Mol Ther 23:434-44 (2015). PubMed: 25399825
  • Yousef H  et al. Systemic attenuation of the TGF-ß pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Oncotarget 6:11959-78 (2015). WB ; Mouse . PubMed: 26003168
  • Bravi L  et al. Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice. Proc Natl Acad Sci U S A 112:8421-6 (2015). PubMed: 26109568
  • Quigley HA  et al. Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. PLoS One 10:e0141137 (2015). PubMed: 26505191
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