Overview

  • Product name

  • Description

    Rabbit polyclonal to SMARCA6
  • Host species

    Rabbit
  • Specificity

    ab192325 detects endogenous levels of SMARCA6 protein.
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human SMARCA6.
    Database link: Q9NRZ9

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab192325 is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab192325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 97 kDa.

Target

  • Function

    Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
  • Tissue specificity

    Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias.
  • Sequence similarities

    Belongs to the SNF2/RAD54 helicase family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localization

    Nucleus. Closely associated with pericentric heterochromatin.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ10339 antibody
    • Helicase lymphoid specific antibody
    • Hells antibody
    • HELLS_HUMAN antibody
    • LSH antibody
    • Lymphoid specific helicase antibody
    • Lymphoid-specific helicase antibody
    • Nbla10143 antibody
    • PASG antibody
    • Proliferation associated SNF2 like protein antibody
    • Proliferation-associated SNF2-like protein antibody
    • SWI/SNF2 related matrix associated actin dependent regulator of chromatin subfamily A member 6 antibody
    • SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6 antibody
    see all

References

ab192325 has not yet been referenced specifically in any publications.

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