Anti-SMC3 antibody - ChIP Grade (ab9263)

Rabbit polyclonal SMC3 antibody. Validated in WB, IP, IHC, ChIP, ICC/IF and tested in Mouse, Human, Xenopus laevis. Cited in 39 publication(s). Independently reviewed in 6 review(s).

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ab9263 has been referenced in 40 publications.

  • Wang T  et al. Smc3 is required for mouse embryonic and adult hematopoiesis. Exp Hematol 70:70-84.e6 (2019). PubMed: 30553776
  • Tsai PF  et al. A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans. Mol Cell 71:129-141.e8 (2018). PubMed: 29979962
  • Casey AE  et al. Differential cohesin loading marks paired and unpaired regions of platypus sex chromosomes at prophase I. Sci Rep 7:4217 (2017). PubMed: 28652620
  • Braikia FZ  et al. Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching. Proc Natl Acad Sci U S A 114:6092-6097 (2017). PubMed: 28533409
  • Schwarzer W  et al. Two independent modes of chromatin organization revealed by cohesin removal. Nature 551:51-56 (2017). PubMed: 29094699
  • Zhang J  et al. Distinct TERB1 Domains Regulate Different Protein Interactions in Meiotic Telomere Movement. Cell Rep 21:1715-1726 (2017). PubMed: 29141207
  • Leonetti MD  et al. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proc Natl Acad Sci U S A 113:E3501-8 (2016). PubMed: 27274053
  • Kylie K  et al. Dynamic regulation of histone H3K9 is linked to the switch between replication and transcription at the Dbf4 origin-promoter locus. Cell Cycle 15:2321-35 (2016). PubMed: 27341472
  • Stelloh C  et al. The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing. Epigenetics Chromatin 9:14 (2016). PubMed: 27087855
  • Mullenders J  et al. Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. J Exp Med 212:1833-50 (2015). WB . PubMed: 26438359
  • Balog J  et al. Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4. Epigenetics 10:1133-42 (2015). ChIP . PubMed: 26575099
  • Lavagnolli T  et al. Initiation and maintenance of pluripotency gene expression in the absence of cohesin. Genes Dev 29:23-38 (2015). WB . PubMed: 25561493
  • Mazumdar C  et al. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell 17:675-688 (2015). CHIPseq . PubMed: 26607380
  • Kracker S  et al. An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex. J Allergy Clin Immunol 135:998-1007.e6 (2015). PubMed: 25312759
  • Qiu Z  et al. Functional interactions between NURF and Ctcf regulate gene expression. Mol Cell Biol 35:224-37 (2015). PubMed: 25348714
  • Ing-Simmons E  et al. Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin. Genome Res 25:504-13 (2015). WB ; Mouse . PubMed: 25677180
  • Alabert C  et al. Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components. Nat Cell Biol 16:281-93 (2014). PubMed: 24561620
  • Ishiguro K  et al. Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes. Genes Dev 28:594-607 (2014). WB ; Mouse . PubMed: 24589552
  • Yun WJ  et al. The hematopoietic regulator TAL1 is required for chromatin looping between the ß-globin LCR and human ?-globin genes to activate transcription. Nucleic Acids Res 42:4283-93 (2014). ChIP ; Human . PubMed: 24470145
  • Chen HS  et al. Epigenetic deregulation of the LMP1/LMP2 locus of Epstein-Barr virus by mutation of a single CTCF-cohesin binding site. J Virol 88:1703-13 (2014). PubMed: 24257606
  • Winters T  et al. Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion. EMBO J 33:1256-70 (2014). PubMed: 24797474
  • Hopkins J  et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet 10:e1004413 (2014). IP, WB, ICC/IF ; Mouse . PubMed: 24992337
  • Court F  et al. The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus. Epigenetics Chromatin 7:5 (2014). ChIP . PubMed: 24667089
  • Sundaramoorthy S  et al. Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion. EMBO J N/A:N/A (2014). WB . PubMed: 25257310
  • Fukuda T  et al. STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J 33:1243-55 (2014). PubMed: 24797475
  • Iglesias-Platas I  et al. Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop. Nucleic Acids Res 41:2171-9 (2013). ChIP ; Human . PubMed: 23295672
  • Li W  et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 498:516-20 (2013). PubMed: 23728302
  • Hahn M  et al. Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin. Genes Dev 27:859-72 (2013). ChIP . PubMed: 23599346
  • Moralli D  et al. Comparative study of artificial chromosome centromeres in human and murine cells. Eur J Hum Genet 21:948-56 (2013). ICC/IF . PubMed: 23403904
  • Prenzel T  et al. Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene. Epigenetics Chromatin 5:13 (2012). WB . PubMed: 22913342
  • Brown AC  et al. Epigenetic regulation of the latency-associated region of Marek's disease virus in tumor-derived T-cell lines and primary lymphoma. J Virol 86:1683-95 (2012). ChIP . PubMed: 22090140
  • Fukuda T  et al. Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS Genet 8:e1002485 (2012). PubMed: 22346761
  • Ishiguro K  et al. A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing. EMBO Rep 12:267-75 (2011). WB ; Mouse . PubMed: 21274006
  • Nativio R  et al. Disruption of genomic neighbourhood at the imprinted IGF2-H19 locus in Beckwith-Wiedemann syndrome and Silver-Russell syndrome. Hum Mol Genet 20:1363-74 (2011). ChIP ; Human . PubMed: 21282187
  • Xiao T  et al. Specific Sites in the C Terminus of CTCF Interact with the SA2 Subunit of the Cohesin Complex and Are Required for Cohesin-Dependent Insulation Activity. Mol Cell Biol 31:2174-83 (2011). WB ; Human . PubMed: 21444719
  • Fukuda T  et al. A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes. Exp Cell Res 316:158-71 (2010). PubMed: 19686734
  • Ebmeier CC & Taatjes DJ Activator-Mediator binding regulates Mediator-cofactor interactions. Proc Natl Acad Sci U S A 107:11283-8 (2010). WB ; Human . PubMed: 20534441
  • Yao H  et al. Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA. Genes Dev 24:2543-55 (2010). ChIP ; Human . PubMed: 20966046
  • Bekker-Jensen S  et al. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173:195-206 (2006). ICC/IF ; Human . PubMed: 16618811
  • Seitan VC  et al. Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance. PLoS Biol 4:e242 (2006). PubMed: 16802858

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