Key features and details
- Rabbit polyclonal to SMG7
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SMG7 antibody
See all SMG7 primary antibodies
DescriptionRabbit polyclonal to SMG7
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to a region within amino acids 719-1003 of Human SMG7, isoform 4 (AAH36381).
- NT2D1 whole cell lysate; HeLa xenograft tissue
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: PBS, 1% BSA, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab126984 in the following tested applications.
|WB||1/500 - 1/3000. Predicted molecular weight: 132 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionPlays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
Sequence similaritiesContains 2 TPR repeats.
Cellular localizationCytoplasm. Nucleus. Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm.
- Information by UniProt
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ab126984 has not yet been referenced specifically in any publications.