Anti-smooth muscle Myosin heavy chain 11 antibody [1G12] (ab683)

Thank you for contacting Abcam.

Please find links below to a few antibodies that we have that recognize smooth muscle heavy chain 1 and 2:

https://www.abcam.com/Myosin-smooth-muscle-heavy-chain-1-and-2-antibody-EPR5335-ab124679.html
https://www.abcam.com/Myosin-smooth-muscle-heavy-chain-1-and-2-antibody-V-10-ab77967.html



Since neither, of these antibodies have been tested in either human and mouse or validated in ICC/IF on cultured cells, you may be able to take advantage of out testing discount program:

https://www.abcam.com/index.html?pageconfig=resource&rid=11998&viapagetrap=collaborationdiscount



Please let me know if there is anything else I can help you with or if you would like to take advantage of the testing discount program.

Thank you for contacting us.

The antibody ab683 will recognize SM2A and SM2B:

Human SM2A

http://www.ncbi.nlm.nih.gov/protein/13124875?report=genbank&log$=prottop&blast_rank=8&RID=R93GH1VT016

Human SM2B

http://www.ncbi.nlm.nih.gov/protein/92091583?report=genbank&log$=prottop&blast_rank=10&RID=R93GH1VT016

It will not recognize SM1A or SM1B, but it cannot distinguish between the A and B isoforms of SM2.

For an antibody specific for SM1, we have ab682. This will not react with SM2, but it cannot distinguish between the A and B isoforms of SM1.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for contacting us.

Yes, I'd be happy to replace ab683 with ab53219 (which is also an Anti-smooth muscle Myosin heavy chain 11 antibody). Since this antibody has not been tested in human samples, we would not be able to guarantee it for human samples. Thus, the Abpromise guarantee would not apply. However, I can issue a testing discount code for the customer. For more details on this offer, please see below.



For UNTESTED species and/or applications, we have established a testing discount program. Here is a brief description of how it works:
The testing discount program is for customers who like to use an antibody/protein on an untested species/application. You would purchase the antibody at full price, test it and submit an Abreview with your data (positive or negative). On your next order you will receive a discount for ONE antibody at the full price (100%) of the antibody you have tested. The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.


Please let me know if the customer would like to receive the testing discount code.


I look forward to hear back from you and assist you further.

Les anticorps ab682 et ab683 ne sont pas purifié et donc la concentration n’a pas été déterminée. Ces anticorps sont des ascites et nous estimons les concentrations d’être entre 5-10 mg/ml.

Thank you for contacting us.

Please find attached protocol for ab7817.

The IHC-P protocol for ab683 can be found in publication;

http://ops.adminsite.com/admin/abcamshare/CRM/attach/2013/3/1/CCE4718082_img-301091703.pdf

The protocol for ab32575 can be found at the link http://www.epitomics.com/products/support/ihc

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for contacting us.

Your credit note ID for the refund is xxx.

I am sorry that this antibody did not perform as stated on the datasheet. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact our accounting department so that we may gather the correct information needed for the refund. To avoid confusion, please ensure your accounts department is aware of how the credit note is being used.

Our accounting department can be contacted by email at us.credits@abcam.com or by telephone using the information at the Contact Us link in the top right corner of our website. Please refer to the credit note ID in any correspondence with our accounting department.

The credit note ID is for your reference only and does not automatically guarantee the credit.

I hope this experience will not prevent you from purchasing other products from us in the future. Our Scientific Support team is always at your service, should you require further expert advice.