Anti-SMRP1 antibody - N-terminal (ab136688)

Overview

  • Product name
    Anti-SMRP1 antibody - N-terminal
  • Description
    Rabbit polyclonal to SMRP1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MFLFSRKTRT PISTYSDSYR APTSIKEVYK DPPLCAWEAN KFLTPGLTHT) of Human SMRP1 (NP_115985). .

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab136688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 30 kDa.

Target

  • Function
    May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells.
  • Tissue specificity
    Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane. Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level).
  • Sequence similarities
    Belongs to the SMRP1 family.
  • Developmental stage
    Expressed during in vitro differentiation of bronchial epithelial cells. In fetal lung, expression is barely detectable at 10 weeks post-conception but is strong in airway epithelium at 12.3 weeks post-conception.
  • Cellular localization
    Cytoplasm > cytoskeleton. Nucleus. Cytoplasm. Localizes to the manchette in elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA573M23.4 antibody
    • C9orf24 antibody
    • CBE1 antibody
    • Chromosome 9 open reading frame 24 antibody
    • Ciliated bronchial epithelial protein 1 antibody
    • Ciliated bronchial epithelium 1 antibody
    • NYD SP22 antibody
    • Smrp1 antibody
    • SMRP1_HUMAN antibody
    • Spermatid-specific manchette-related protein 1 antibody
    • Testis development protein NYD-SP22 antibody
    see all

Images

  • Anti-SMRP1 antibody - N-terminal (ab136688) at 1 µg/ml + HeLa whole cell lysate at 10 µg

    Predicted band size: 30 kDa

References

ab136688 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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