Anti-SNAIL + SLUG antibody (ab180714)

Rabbit polyclonal SNAIL + SLUG antibody. Validated in WB, IHC, ICC/IF and tested in Mouse, Rat, Human. Cited in 59 publication(s). Independently reviewed in 6 review(s).

Publishing research using ab180714? Please let us know so that we can cite the reference in this datasheet.

ab180714 has been referenced in 63 publications.

  • Dai J  et al. Matrix stiffness regulates epithelial-mesenchymal transition via cytoskeletal remodeling and MRTF-A translocation in osteosarcoma cells. J Mech Behav Biomed Mater 90:226-238 (2019). PubMed: 30384218
  • Chen S  et al. RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment. J Exp Clin Cancer Res 38:15 (2019). PubMed: 30630537
  • Yanchun M  et al. Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway. Eur J Pharmacol 851:43-51 (2019). PubMed: 30779917
  • Fujiwara S  et al. Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas. Cancer Med 8:1671-1678 (2019). PubMed: 30791220
  • Singh R  et al. Positive Correlation between Matrix Metalloproteinases and Epithelial-to-Mesenchymal Transition and its Association with Clinical Outcome in Bladder Cancer Patients. Cancer Microenviron 11:23-39 (2018). PubMed: 29349669
  • Sun JX  et al. SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization. Angiogenesis 21:635-652 (2018). PubMed: 29675549
  • Kaowinn S  et al. STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2. Oncol Rep 40:2619-2627 (2018). PubMed: 30226605
  • Životic M  et al. Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells. PLoS One 13:e0206786 (2018). PubMed: 30383875
  • Yang Y  et al. Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer. Sci Rep 8:16234 (2018). PubMed: 30390003
  • Liu GM  et al. Restoration of FBP1 suppressed Snail-induced epithelial to mesenchymal transition in hepatocellular carcinoma. Cell Death Dis 9:1132 (2018). PubMed: 30429463
  • Ito N  et al. Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency. Sci Rep 8:1634 (2018). PubMed: 29374279
  • Jeong BY  et al. Rab25 augments cancer cell invasiveness through a ß1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin. Exp Mol Med 50:e435 (2018). IHC . PubMed: 29371698
  • Wang X  et al. Cancer-associated fibroblasts induce epithelial-mesenchymal transition through secreted cytokines in endometrial cancer cells. Oncol Lett 15:5694-5702 (2018). PubMed: 29563996
  • Taki M  et al. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation. Nat Commun 9:1685 (2018). PubMed: 29703902
  • Zhao Y  et al. An essential role for Wnt/ß-catenin signaling in mediating hypertensive heart disease. Sci Rep 8:8996 (2018). WB ; Rat . PubMed: 29895976
  • Sun M  et al. MicroRNA-378 regulates epithelial-mesenchymal transition and metastasis of melanoma by inhibiting FOXN3 expression through the Wnt/ß-catenin pathway. Cell Biol Int N/A:N/A (2018). PubMed: 29972255
  • Oyanadel C  et al. Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells. Mol Biol Cell 29:557-574 (2018). PubMed: 29298841
  • Wang M  et al. Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/ß-catenin pathway against renal fibrosis. Br J Pharmacol 175:2689-2708 (2018). PubMed: 29679507
  • Hong KO  et al. Tumor budding is associated with poor prognosis of oral squamous cell carcinoma and histologically represents an epithelial-mesenchymal transition process. Hum Pathol N/A:N/A (2018). PubMed: 29936060
  • Wei R  et al. In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer. J Cell Mol Med 22:4097-4105 (2018). PubMed: 29851214
  • He WM  et al. Oleanolic acid attenuates TGF-ß1-induced epithelial-mesenchymal transition in NRK-52E cells. BMC Complement Altern Med 18:205 (2018). PubMed: 29973206
  • Xu X  et al. PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion. J Exp Clin Cancer Res 37:158 (2018). PubMed: 30016974
  • Sun H  et al. Anti-angiogenic treatment promotes triple-negative breast cancer invasion via vasculogenic mimicry. Cancer Biol Ther 18:205-213 (2017). PubMed: 28278077
  • Mahmoud MM  et al. Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. Sci Rep 7:3375 (2017). IHC ; Mouse . PubMed: 28611395
  • Wu KQ  et al. M1 Macrophage-Induced Endothelial-to-Mesenchymal Transition Promotes Infantile Hemangioma Regression. Am J Pathol 187:2102-2111 (2017). PubMed: 28710904
  • Yang S  et al. STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling. Oncotarget 8:5976-5991 (2017). WB ; Human . PubMed: 27863406
  • Jaca A  et al. The role of miRNA-21 and epithelial mesenchymal transition (EMT) process in colorectal cancer. J Clin Pathol 70:331-356 (2017). Human . PubMed: 27672217
  • Deneka AY  et al. Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model. PLoS One 12:e0176747 (2017). WB ; Mouse . PubMed: 28453558
  • Saito H  et al. Potential of extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational study. BMC Cancer 17:294 (2017). IHC-P ; Human . PubMed: 28449652
  • Bian XL  et al. Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nat Commun 8:14420 (2017). PubMed: 28240261
  • Quattrocelli M  et al. Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury. PLoS Genet 13:e1007070 (2017). PubMed: 29065150
  • Mao XW  et al. CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/ß-catenin signaling pathway. Oncotarget 8:77241-77253 (2017). PubMed: 29100384
  • Suffee N  et al. Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria. Proc Natl Acad Sci U S A 114:E771-E780 (2017). PubMed: 28096344
  • Lu J  et al. IKBKE regulates cell proliferation and epithelial-mesenchymal transition of human malignant glioma via the Hippo pathway. Oncotarget 8:49502-49514 (2017). PubMed: 28548934
  • Mahmood MQ  et al. ß-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction. Sci Rep 7:10832 (2017). PubMed: 28883453
  • Feng X  et al. Expression of EMT markers and mode of surgery are prognostic in phyllodes tumors of the breast. Oncotarget 8:33365-33374 (2017). PubMed: 28380418
  • Wu BQ  et al. Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells. Technol Cancer Res Treat N/A:1533034617700559 (2017). PubMed: 28355965
  • Mitchell B  et al. BRAF and epithelial-mesenchymal transition in papillary thyroid carcinoma - challenging the roles of Snail and E-Cadherin? Am J Transl Res 8:5076-5086 (2016). IHC-P ; Human . PubMed: 27904709
  • Zhou W  et al. Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis. Sci Rep 6:38646 (2016). WB ; Mouse . PubMed: 27982105
  • Wei MG  et al. JiaWeiDangGui Decoction Ameliorates Proteinuria and Kidney Injury in Adriamycin-Induced Rat by Blockade of TGF-ß/Smad Signaling. Evid Based Complement Alternat Med 2016:5031890 (2016). WB ; Rat . PubMed: 27403197
  • Tanaka N  et al. Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation. JCI Insight 1:e83654 (2016). PubMed: 27812537
  • Ma X  et al. Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/ß-catenin pathway. Drug Des Devel Ther 10:1419-41 (2016). PubMed: 27143851
  • Ding H  et al. Glioma-associated oncogene homolog 1 promotes epithelial-mesenchymal transition in human renal tubular epithelial cell. Am J Transl Res 8:662-9 (2016). WB ; Human . PubMed: 27158358
  • Bai X  et al. MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy. Sci Rep 6:20475 (2016). WB . PubMed: 26837280
  • Kugler J  et al. Editor's Highlight: Identification and Characterization of Teratogenic Chemicals Using Embryonic Stem Cells Isolated From a Wnt/ß-Catenin-Reporter Transgenic Mouse Line. Toxicol Sci 152:382-94 (2016). ICC/IF ; Mouse . PubMed: 27208078
  • Kudinov AE  et al. Musashi-2 (MSI2) supports TGF-ß signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis. Proc Natl Acad Sci U S A 113:6955-60 (2016). WB . PubMed: 27274057
  • Li C  et al. Overexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial-mesenchymal transition-induced angiogenesis. Cancer Gene Ther 23:295-302 (2016). WB ; Human . PubMed: 27492854
  • Tan H  et al. miR-382 inhibits migration and invasion by targeting ROR1 through regulating EMT in ovarian cancer. Int J Oncol 48:181-90 (2016). PubMed: 26575700
  • Blanco S  et al. Stem cell function and stress response are controlled by protein synthesis. Nature 534:335-40 (2016). WB ; Mouse . PubMed: 27306184
  • Fang S  et al. Cisplatin promotes mesenchymal-like characteristics in osteosarcoma through Snail. Oncol Lett 12:5007-5014 (2016). WB . PubMed: 28105207
  • Feng D  et al. Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis. Oncotarget 7:64575-64588 (2016). WB ; Human . PubMed: 27602489
  • Li Y  et al. Autocrine motility factor promotes epithelial-mesenchymal transition in endometrial cancer via MAPK signaling pathway. Int J Oncol 47:1017-24 (2015). PubMed: 26201353
  • Zheng X  et al. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527:525-30 (2015). IHC-P ; Mouse . PubMed: 26560028
  • Cicchini C  et al. Epigenetic control of EMT/MET dynamics: HNF4a impacts DNMT3s through miRs-29. Biochim Biophys Acta 1849:919-29 (2015). ICC/IF . PubMed: 26003733
  • Piskareva O  et al. The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro. Cancer Lett N/A:N/A (2015). PubMed: 25960282
  • Xie B  et al. DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1. J Exp Clin Cancer Res 34:101 (2015). IHC-P ; Human . PubMed: 26362312
  • Yin X  et al. Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling. J Hematol Oncol 8:23 (2015). WB . PubMed: 25879771
  • Li Z  et al. The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer. J Transl Med 13:84 (2015). WB, IF ; Human . PubMed: 25889214
  • Wei MG  et al. Ferulic Acid Attenuates TGF-ß1-Induced Renal Cellular Fibrosis in NRK-52E Cells by Inhibiting Smad/ILK/Snail Pathway. Evid Based Complement Alternat Med 2015:619720 (2015). WB ; Rat . PubMed: 25949265
  • Xu X  et al. Snail Is a Direct Target of Hypoxia-inducible Factor 1a (HIF1a) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells. J Biol Chem 290:16653-64 (2015). PubMed: 25971970
  • Qin W  et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget 6:39839-54 (2015). WB ; Human . PubMed: 26497999
  • Jiang FZ  et al. Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing. Oncotarget 6:44660-74 (2015). ICC/IF . PubMed: 26587974
  • Xiang Z  et al. CXCL1 expression is correlated with Snail expression and affects the prognosis of patients with gastric cancer. Oncol Lett 10:2458-2464 (2015). IHC-P ; Human . PubMed: 26622871

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