SNAP, NO donor (ab120014)
- Datasheet
- References (6)
Overview
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Product name
SNAP, NO donor -
Description
NO donor -
Biological description
NO donor. Vasodilator in vitro and in vivo, that does not induce pharmacological tolerance. -
CAS Number
67776-06-1 -
Chemical structure
Properties
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Chemical name
S-Nitroso-N-acetyl-DL-penicillamin -
Molecular weight
220.24 -
Molecular formula
C7H12N2O4S -
PubChem identifier
5231 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(SN=O)C(NC(=O)C)C(=O)O -
Source
Synthetic
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Research areas
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Nitric oxide & oxidative stress
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
Associated products
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Related Products
References
This product has been referenced in:
- Ignarro LJ et al. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview. Circ Res 90:21-8 (2002). Read more (PubMed: 11786514) »
- Yamamoto T & Bing RJ Nitric oxide donors. Proc Soc Exp Biol Med 225:200-6 (2000). Read more (PubMed: 11082214) »
- Ferrero R et al. Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: correlation with nitric oxide production. Br J Pharmacol 127:779-87 (1999). Read more (PubMed: 10401570) »
- Shaffer JE et al. Lack of tolerance to a 24-hour infusion of S-nitroso N-acetylpenicillamine (SNAP) in conscious rabbits. J Pharmacol Exp Ther 260:286-93 (1992). Read more (PubMed: 1731043) »
