Overview

  • Product name
    Anti-SNAP23 antibody
    See all SNAP23 primary antibodies
  • Description
    Goat polyclonal to SNAP23
  • Host species
    Goat
  • Specificity
    ab166808 is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1).
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human
    Predicted to work with: Monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide:

    QIKRITDKAD

    by a Cysteine residue linker, corresponding to internal sequence amino acids 183-192 of Human SNAP23 (NP_003816.2).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Human placenta lysate; Human spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab166808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 23 kDa).
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
  • Tissue specificity
    Ubiquitous. Highest levels where found in placenta.
  • Sequence similarities
    Belongs to the SNAP-25 family.
    Contains 2 t-SNARE coiled-coil homology domains.
  • Cellular localization
    Cell membrane. Cell membrane. Cell junction, synapse, synaptosome. Mainly localized to the plasma membrane.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • HsT17016 antibody
    • LS-B8340 antibody
    • SNAP 23 antibody
    • SNAP-23 antibody
    • SNAP23 antibody
    • SNAP23A antibody
    • SNAP23B antibody
    • SNP23_HUMAN antibody
    • Synaptosomal associated protein 23 antibody
    • Synaptosomal associated protein 23kDa antibody
    • Synaptosomal associated protein antibody
    • Synaptosomal-associated protein 23 antibody
    • Vesicle membrane fusion protein SNAP 23 antibody
    • Vesicle membrane fusion protein SNAP23 antibody
    • Vesicle-membrane fusion protein SNAP-23 antibody
    see all

Images

  • Western blot - Anti-SNAP23 antibody (ab166808)
    Western blot - Anti-SNAP23 antibody (ab166808)
    Anti-SNAP23 antibody (ab166808) at 0.1 µg/ml + Human Placenta lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 23 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNAP23 antibody (ab166808)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNAP23 antibody (ab166808)
    Immunohistochemical analysis of formalin fixed, paraffin embedded Human spleen tissue labeling SNAP23 with ab166808 antibody at 3.75 µg/ml.

References

This product has been referenced in:
  • da Silva LB  et al. Botulinum neurotoxin type A modulates vesicular release of glutamate from satellite glial cells. J Cell Mol Med 19:1900-9 (2015). ICC, IHC . Read more (PubMed: 25754332) »

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