Anti-SNAP23 antibody (ab166808)
Key features and details
- Goat polyclonal to SNAP23
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Cow, Human
- Isotype: IgG
Overview
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Product name
Anti-SNAP23 antibody
See all SNAP23 primary antibodies -
Description
Goat polyclonal to SNAP23 -
Host species
Goat -
Specificity
ab166808 is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1). -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat, Cow, Human
Predicted to work with: Monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide:
QIKRITDKAD
by a Cysteine residue linker, corresponding to internal sequence amino acids 183-192 of Human SNAP23 (NP_003816.2). -
Positive control
- Human placenta lysate; Human spleen tissue
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab166808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 23 kDa). | |
| IHC-P | Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. -
Tissue specificity
Ubiquitous. Highest levels where found in placenta. -
Sequence similarities
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains. -
Cellular localization
Cell membrane. Cell membrane. Cell junction, synapse, synaptosome. Mainly localized to the plasma membrane. - Information by UniProt
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Database links
- Entrez Gene: 522423 Cow
- Entrez Gene: 101141000 Gorilla
- Entrez Gene: 8773 Human
- Entrez Gene: 20619 Mouse
- Entrez Gene: 100174679 Orangutan
- Entrez Gene: 64630 Rat
- Omim: 602534 Human
- SwissProt: O00161 Human
see all -
Alternative names
- HsT17016 antibody
- LS-B8340 antibody
- SNAP 23 antibody
see all
Images
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Western blot - Anti-SNAP23 antibody (ab166808)Anti-SNAP23 antibody (ab166808) at 0.1 µg/ml + Human Placenta lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 23 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNAP23 antibody (ab166808)Immunohistochemical analysis of formalin fixed, paraffin embedded Human spleen tissue labeling SNAP23 with ab166808 antibody at 3.75 µg/ml.
Protocols
Datasheets and documents
References (1)
ab166808 has been referenced in 1 publication.
- da Silva LB et al. Botulinum neurotoxin type A modulates vesicular release of glutamate from satellite glial cells. J Cell Mol Med 19:1900-9 (2015). ICC, IHC . PubMed: 25754332
