Rat Predicted to work with:
Mouse, Guinea pig, Human, Non human primates, Zebrafish
Synthetic peptide within Rat SNAP25 (phospho S187). The exact sequence is proprietary. Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser187 conjugated to KLH Database link: P60881
Rat hippocampal lysate
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 23 kDa.
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Belongs to the SNAP-25 family. Contains 2 t-SNARE coiled-coil homology domains.
Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association.
Cytoplasm > perinuclear region. Cell membrane. Cell junction > synapse > synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.