• Product name

  • Description

    Rabbit polyclonal to SNAT2
  • Host species

  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SNAT2 aa 1-76.
    Database link: Q96QD8

  • Positive control

    • WB: A431 whole cell lysate. IHC-P: Human small intestine and panceas tissues. ICC/IF: A431 cells.
  • General notes

     This product was previously labelled as SLC38A2




Our Abpromise guarantee covers the use of ab237614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 56 kDa.
IHC-P 1/20 - 1/200.


  • Function

    Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.
  • Tissue specificity

    Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).
  • Sequence similarities

    Belongs to the amino acid/polyamine transporter 2 family.
  • Post-translational

    Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.
  • Cellular localization

    Cell membrane. Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.
  • Information by UniProt
  • Database links

  • Alternative names

    • Amino acid transporter 2 antibody
    • Amino acid transporter A2 antibody
    • ATA2 antibody
    • KIAA1382 antibody
    • PRO1068 antibody
    • Protein 40-9-1 antibody
    • S38A2_HUMAN antibody
    • SAT2 antibody
    • Slc38a2 antibody
    • SNAT2 antibody
    • Sodium-coupled neutral amino acid transporter 2 antibody
    • Solute carrier family 38 member 2 antibody
    • System A amino acid transporter antibody
    • System A amino acid transporter 2 antibody
    • System A transporter 1 antibody
    • System N amino acid transporter 2 antibody
    see all


  • Anti-SNAT2 antibody (ab237614) at 1/500 dilution + A431 (human epidermoid carcinoma cell line) whole cell lysate

    Goat polyclonal to rabbit IgG at 1/10000 dilution

    Predicted band size: 56 kDa

  • Paraffin-embedded human small intestine tissue stained for SNAT2 using ab237614 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human pancreatic tissue stained for SNAT2 using ab237614 at 1/100 dilution in immunohistochemical analysis.

  • A431 (human epidermoid carcinoma cell line) cells stained for SNAT2 (green) using ab237614 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).


This product has been referenced in:

  • Shang M & Wen Z Increased placental IGF-1/mTOR activity in macrosomia born to women with gestational diabetes. Diabetes Res Clin Pract 146:211-219 (2018). Read more (PubMed: 30389621) »
See 1 Publication for this product

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