Overview

  • Product name
  • Description
    Rabbit polyclonal to SNRPB
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-188 of Human SNRPB.

  • Positive control
    • Hela cells; HeLa nuclear lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab155026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 25 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
  • Sequence similarities
    Belongs to the snRNP SmB/SmN family.
  • Post-translational
    modifications
    Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • B polypeptide of Sm protein antibody
    • COD antibody
    • RSMB_HUMAN antibody
    • Sm B/B' antibody
    • Sm B/Sm B' antibody
    • Sm B/SmB' antibody
    • Sm protein B/B'' antibody
    • Sm-B/B'' antibody
    • Small nuclear ribonucleoprotein polypeptide B antibody
    • Small nuclear ribonucleoprotein polypeptide B/B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B1 antibody
    • Small nuclear ribonucleoprotein-associated proteins B and B'' antibody
    • SmB antibody
    • SmB/B'' antibody
    • SmB/Sm B' antibody
    • SmB/SmB' antibody
    • snRNP B antibody
    • snRNP-B antibody
    • snRNPB antibody
    • SNRPB antibody
    • SNRPB1 antibody
    see all

Images

  • Anti-SNRPB antibody (ab155026) at 1/1000 dilution + Hela nuclear lysate at 30 µg

    Predicted band size: 25 kDa



    12% SDS PAGE
  • Confocal immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling SNRPB with ab155026 at 1/500 dilution (Green). Alpha-tubulin filaments were labeled red.

References

ab155026 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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