Overview

  • Product name
  • Description
    Rabbit polyclonal to SNRPB/SmB
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SNRPB/SmB aa 1-188.

  • Positive control
    • Hela cells; HeLa nuclear lysate.
  • General notes

     This product was previously labelled as SNRPB

     

Properties

Applications

Our Abpromise guarantee covers the use of ab155026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 25 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
  • Sequence similarities
    Belongs to the snRNP SmB/SmN family.
  • Post-translational
    modifications
    Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • B polypeptide of Sm protein antibody
    • COD antibody
    • RSMB_HUMAN antibody
    • Sm B/B' antibody
    • Sm B/Sm B' antibody
    • Sm B/SmB' antibody
    • Sm protein B/B'' antibody
    • Sm-B/B'' antibody
    • Small nuclear ribonucleoprotein polypeptide B antibody
    • Small nuclear ribonucleoprotein polypeptide B/B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B' antibody
    • Small nuclear ribonucleoprotein polypeptides B and B1 antibody
    • Small nuclear ribonucleoprotein-associated proteins B and B'' antibody
    • SmB antibody
    • SmB/B'' antibody
    • SmB/Sm B' antibody
    • SmB/SmB' antibody
    • snRNP B antibody
    • snRNP-B antibody
    • snRNPB antibody
    • SNRPB antibody
    • SNRPB1 antibody
    see all

Images

  • Anti-SNRPB/SmB antibody (ab155026) at 1/1000 dilution + Hela nuclear lysate at 30 µg

    Predicted band size: 25 kDa



    12% SDS PAGE
  • Confocal immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling SNRPB/SmB with ab155026 at 1/500 dilution (Green). Alpha-tubulin filaments were labeled red.

References

ab155026 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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