Overview

  • Product name

  • Description

    Rabbit polyclonal to SNX19
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 625-750 of Human SNX19.

  • Positive control

    • Human kidney tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform Heat Induced Epitope Retrieval (HIER) at pH 6 using a pressure boiler as heat source.

Target

  • Function

    May be involved in several stages of intracellular trafficking.
  • Sequence similarities

    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
    Contains 1 PXA domain.
  • Domain

    The PX domain mediates specific binding to membranes enriched in phosphatidylinositol-3-phosphate (PtdIns(P3)).
  • Cellular localization

    Cytoplasmic vesicle membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • SNX19 antibody
    • SNX19_HUMAN antibody
    • Sorting nexin 19 antibody
    • Sorting nexin-19 antibody

Images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in mitochondria. Recommended concentration of ab121401 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121401 at 1/75 dilution staining SNX19 in Paraffin-embedded Human Kidney tissue by Immunohistochemistry.
    Note: strong cytoplasmic positivity in cells in tubules.

References

ab121401 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab121401.
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