Key features and details
- Chicken polyclonal to SNX2
- Suitable for: WB, ICC
- Reacts with: Mouse, Rat, Human
- Isotype: IgY
Product nameAnti-SNX2 antibody
See all SNX2 primary antibodies
DescriptionChicken polyclonal to SNX2
Tested applicationsSuitable for: WB, ICCmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide, corresponding to amino acids 12/138 of Human SNX2
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab26201 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 58 kDa.|
FunctionMay be involved in several stages of intracellular trafficking. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
Sequence similaritiesBelongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Cellular localizationEarly endosome membrane.
- Information by UniProt
- MGC5204 antibody
- SNX 2 antibody
- SNX2 antibody
Subcellular localisation of SNX2 in human HeLa cells using ab26201 and an anti-chicken-Cy3 conjugated secondary antibody (Red). Nuclear staining with DAPI (Blue).
All lanes : Anti-SNX2 antibody (ab26201) at 1/1000 dilution
All lanes : HeLa whole cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : HRP conjugated sheep anti-chicken IgG
Predicted band size: 58 kDa
Observed band size: ~60 kDa why is the actual band size different from the predicted?
ab26201 strongly detects SNX2 at ~60kDa and at long exposures smaller weak bands (potentially degradation products of SNX2).
ab26201 has been referenced in 1 publication.
- Spooner E et al. Systematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1. PLoS One 8:e56780 (2013). WB ; Mouse . PubMed: 23418601