Overview

  • Product name

  • Description

    Rabbit polyclonal to Snx6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 312-361 (LRESQAAKDL LYRRSRSLVD YENANKALDK ARAKNKDVLQ AETSQQLCCQ) of Human Snx6 (NP_689419).

  • Positive control

    • Human placenta lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab131010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.

Target

  • Relevance

    Snx6 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
  • Cellular localization

    Endosomes
  • Database links

  • Alternative names

    • Sorting Nexin 6 antibody
    • TFAF2 antibody
    • TRAF4 Associated Factor 2 antibody

Images

  • Western blot analysis of Hela (lane 1) NIHT3 (lane 2) and IHKE1 (lane 3) cell lysates (40µg/lane) labeling Snx6 with ab131010 at 1:1000. A HRP-conjugated Goat anti-rabbit IgG (1:1000) was used as the secondary antibody.
  • Anti-Snx6 antibody (ab131010) at 1 µg/ml + Human placenta lysate at 10 µg

    Predicted band size: 48 kDa

References

ab131010 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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