Overview

  • Product name
  • Description
    Goat polyclonal to SNX8
  • Host species
    Goat
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    TPPCSPPEDGLCPH

    , corresponding to C terminal amino acids 452-465 of Human SNX8.

  • Positive control
    • Jurkat and Human Liver extracts.
  • General notes
    GenBank Accession Number – NP_037453.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab5988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Target

  • Function
    May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.
  • Sequence similarities
    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
  • Cellular localization
    Early endosome membrane. Colocalizes with retromer components.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp761E1721 antibody
    • Highly similar to MVP1 PROTEIN Saccharomyces cerevisiae antibody
    • Mvp1 antibody
    • OTTHUMP00000200137 antibody
    • SNX 8 antibody
    • SNX8 antibody
    • SNX8_HUMAN antibody
    • Sorting nexin 8 antibody
    • Sorting nexin-8 antibody
    see all

Images

  • ab5988 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows vesicular staining in the cytoplasm of preferentially DCT epithelial cells.

References

ab5988 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab5988.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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