Anti-SOD2/MnSOD antibody (ab13533)

ab13533 has been referenced in 88 publications.

• Jeong BY  et al. Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury. PLoS One 13:e0191034 (2018). PubMed: 29329317
• Pinteric M  et al. De novo expression of transfected sirtuin 3 enhances susceptibility of human MCF-7 breast cancer cells to hyperoxia treatment. Free Radic Res N/A:1-13 (2018). PubMed: 29683756
• Orešcanin-Dušic Z  et al. The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes. Oxid Med Cell Longev 2018:5969486 (2018). PubMed: 29599898
• Pi Z  et al. Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. Mol Med Rep 17:6497-6505 (2018). PubMed: 29488606
• Liu Y  et al. Ameliorative effects of Antrodia cinnamomea polysaccharides against cyclophosphamide-induced immunosuppression related to Nrf2/HO-1 signaling in BALB/c mice. Int J Biol Macromol 116:8-15 (2018). WB ; Mouse . PubMed: 29730008
• Shi Z  et al. Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction. Biomed Res Int 2018:2708491 (2018). PubMed: 29765980
• Rabelo-Santos SH  et al. Strong SOD2 expression and HPV-16/18 positivity are independent events in cervical cancer. Oncotarget 9:21630-21640 (2018). PubMed: 29774090
• Zhao D  et al. Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice. Oxid Med Cell Longev 2018:4079041 (2018). PubMed: 29849892
• Zeng N  et al. Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. Exp Gerontol 110:23-34 (2018). WB . PubMed: 29751091
• Zhao XL & Yu CZ Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway. Chem Biol Interact 290:57-63 (2018). WB ; Human . PubMed: 29800573
• Stancic A  et al. A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection. Comp Biochem Physiol B Biochem Mol Biol 219-220:1-9 (2018). WB . PubMed: 29501789
• Tawiah A  et al. High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells. Am J Pathol 188:1354-1373 (2018). WB . PubMed: 29545196
• Li Y  et al. A chlorogenic acid-phospholipid complex ameliorates post-myocardial infarction inflammatory response mediated by mitochondrial reactive oxygen species in SAMP8 mice. Pharmacol Res 130:110-122 (2018). WB . PubMed: 29408518
• Szelechowski M  et al. Metabolic Reprogramming in Amyotrophic Lateral Sclerosis. Sci Rep 8:3953 (2018). PubMed: 29500423
• Volodina O  et al. Short-term heat stress alters redox balance in porcine skeletal muscle. Physiol Rep 5:N/A (2017). PubMed: 28455453
• Yu EPK  et al. Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness. Arterioscler Thromb Vasc Biol 37:2322-2332 (2017). WB ; Human . PubMed: 28970293
• Dunham J  et al. Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey. PLoS One 12:e0188013 (2017). ICC/IF ; Monkey . PubMed: 29136024
• Katare PB  et al. Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats. Front Immunol 8:719 (2017). PubMed: 28690610
• Zhang W  et al. Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction. Oxid Med Cell Longev 2017:4082102 (2017). PubMed: 29209448
• Karwaciak I  et al. TLR2 activation induces antioxidant defence in human monocyte-macrophage cell line models. Oncotarget 8:54243-54264 (2017). PubMed: 28903338
• Buck E  et al. Comparison of Sirtuin 3 Levels in ALS and Huntington's Disease-Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models. Front Mol Neurosci 10:156 (2017). WB . PubMed: 28603486
• Bodega G  et al. The Antioxidant Machinery of Young and Senescent Human Umbilical Vein Endothelial Cells and Their Microvesicles. Oxid Med Cell Longev 2017:7094781 (2017). WB ; Human . PubMed: 28642812
• Azimzadeh O  et al. A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers. Oncotarget 8:9067-9078 (2017). WB . PubMed: 27391067
• Chavan H  et al. Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response. Oxid Med Cell Longev 2017:9251303 (2017). WB ; Human . PubMed: 28163822
• Biswal MR  et al. Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD. Invest Ophthalmol Vis Sci 58:1237-1245 (2017). WB ; Mouse . PubMed: 28241311
• Martinez L  et al. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer 16:559 (2016). WB . PubMed: 27473585
• Carlson RI  et al. Development and application of an antibody-based protein microarray to assess physiological stress in grizzly bears (Ursus arctos). Conserv Physiol 4:cow001 (2016). Other species . PubMed: 27293753
• Greco T  et al. Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity. J Cereb Blood Flow Metab 36:1603-13 (2016). PubMed: 26661201
• Kim J  et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener 11:55 (2016). WB ; Human . PubMed: 27456084
• Lee WH  et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. Elife 5:N/A (2016). WB ; Mouse . PubMed: 27863209
• Zhang X  et al. PGC-1a/ERRa-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase ß. Antioxid Redox Signal 24:312-28 (2016). PubMed: 26421366
• Jian Z  et al. CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability. EMBO Mol Med 8:813-29 (2016). PubMed: 27286733
• Wang R  et al. Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner. Aging (Albany NY) 8:1184-200 (2016). WB . PubMed: 27221200
• Mot AI  et al. Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture. Int J Biochem Cell Biol 79:128-138 (2016). PubMed: 27590850
• Tweedie D  et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. PLoS One 11:e0156493 (2016). PubMed: 27254111
• Safdar A  et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle 6:7 (2016). WB . PubMed: 26834962
• Nguyen TT  et al. Scavengers of reactive ?-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7. Aging (Albany NY) 8:1759-80 (2016). WB . PubMed: 27514077
• Santi A  et al. Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth. Biochim Biophys Acta 1853:3211-23 (2015). PubMed: 26384873
• Lauritzen KH  et al. Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. Am J Physiol Heart Circ Physiol 309:H434-49 (2015). PubMed: 26055793
• Macanovic B  et al. Correlation between sperm parameters and protein expression of antioxidative defense enzymes in seminal plasma: a pilot study. Dis Markers 2015:436236 (2015). PubMed: 25691806
• Xiong W  et al. NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage. J Clin Invest 125:1433-45 (2015). IHC-Fr ; Mouse . PubMed: 25798616
• Moghimi E  et al. Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral Sclerosis. PLoS One 10:e0126355 (2015). WB ; Mouse . PubMed: 26020962
• Wang P  et al. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget 6:21148-58 (2015). Human . PubMed: 26020803
• Cherry AD  et al. Peroxisome proliferator-activated receptor ? co-activator 1-a as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis. J Biol Chem 289:41-52 (2014). WB ; Mouse . PubMed: 24253037
• Salisbury TB  et al. Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells. Biochem Pharmacol 91:390-9 (2014). PubMed: 24971714
• Fiesel FC  et al. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci 127:3488-504 (2014). PubMed: 24928900
• Berhane H  et al. Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice. Radiat Res 181:76-89 (2014). PubMed: 24397476
• Morten KJ  et al. Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts. J Pathol 229:755-64 (2013). WB . PubMed: 23303559
• Zhou L  et al. The role of RING box protein 1 in mouse oocyte meiotic maturation. PLoS One 8:e68964 (2013). PubMed: 23874827
• Gammon L  et al. Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism. PLoS One 8:e62493 (2013). WB . PubMed: 23638097
• Koga K  et al. Macrophage migration inhibitory factor antagonizes pressure overload-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol 304:H282-93 (2013). WB ; Mouse . PubMed: 23144312
• Losón OC  et al. Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell 24:659-67 (2013). WB ; Human . PubMed: 23283981
• Banduseela VC  et al. Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle. Physiol Genomics 45:477-86 (2013). PubMed: 23572537
• Raju I  et al. FoxO3a Serves as a Biomarker of Oxidative Stress in Human Lens Epithelial Cells under Conditions of Hyperglycemia. PLoS One 8:e67126 (2013). PubMed: 23805295
• Gill T & Levine AD Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. J Biol Chem 288:26246-55 (2013). PubMed: 23880762
• Pereira L  et al. Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. EMBO Mol Med 5:1759-74 (2013). WB ; Human . PubMed: 24115572
• Zhu WJ  et al. Amelioration of cardio-renal injury with aging in dahl salt-sensitive rats by H2-enriched electrolyzed water. Med Gas Res 3:26 (2013). WB ; Rat . PubMed: 24289332
• Kang C & Ji LL Muscle immobilization and remobilization downregulates PGC-1a signaling and the mitochondrial biogenesis pathway. J Appl Physiol (1985) 115:1618-25 (2013). WB ; Mouse . PubMed: 23970536
• Pohjoismäki JL  et al. Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response. Nucleic Acids Res 40:6595-607 (2012). WB ; Rat . PubMed: 22508755
• Gilbert JS  et al. Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. Hypertension 60:1545-51 (2012). PubMed: 23090773
• Mahne S  et al. Environmentally persistent free radicals decrease cardiac function and increase pulmonary artery pressure. Am J Physiol Heart Circ Physiol 303:H1135-42 (2012). PubMed: 22942180
• Woolston CM  et al. The prognostic and predictive power of redox protein expression for anthracycline-based chemotherapy response in locally advanced breast cancer. Mod Pathol 25:1106-16 (2012). IHC . PubMed: 22481283
• Yang Y  et al. A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer. Cancer Genet 205:377-90 (2012). PubMed: 22867999
• Aare S  et al. Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model. Physiol Genomics 44:865-77 (2012). PubMed: 22851759
• Powell KA  et al. Mitochondrial localization and ocular expression of mutant Opa3 in a mouse model of 3-methylglutaconicaciduria type III. Invest Ophthalmol Vis Sci 52:4369-80 (2011). PubMed: 21613372
• Narayanan A  et al. Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection. PLoS One 6:e20354 (2011). WB . PubMed: 21655261
• Chan NC  et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20:1726-37 (2011). WB ; Human . PubMed: 21296869
• Bewley MA  et al. Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae. Mol Cell Proteomics 10:M111.008193 (2011). WB ; Human . PubMed: 21474794
• Herring A  et al. Exercise during pregnancy mitigates Alzheimer-like pathology in mouse offspring. FASEB J : (2011). Mouse . PubMed: 21948247
• Szego EM  et al. Estrogen regulates cytoskeletal flexibility, cellular metabolism and synaptic proteins: A proteomic study. Psychoneuroendocrinology 35:807-19 (2010). WB, IHC-FoFr ; Mouse . PubMed: 20005634
• Bigi A  et al. Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively. Glycobiology 20:148-57 (2010). WB ; African green monkey . PubMed: 19797320
• Yang Y  et al. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet 196:45-55 (2010). PubMed: 19963135
• Safdar A  et al. Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults. PLoS One 5:e10778 (2010). WB, IP . PubMed: 20520725
• Ahmad M  et al. Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD. Am J Physiol Heart Circ Physiol 297:H1453-61 (2009). PubMed: 19666846
• Ghosh R  et al. Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development. Transl Oncol 2:65-72 (2009). IHC-P ; Rat . PubMed: 19412421
• Zandi F  et al. Proteomics analysis of BHK-21 cells infected with a fixed strain of rabies virus. Proteomics 9:2399-407 (2009). WB . PubMed: 19322775
• Azarashvili T  et al. Ca2+-dependent permeability transition regulation in rat brain mitochondria by 2',3'-cyclic nucleotides and 2',3'-cyclic nucleotide 3'-phosphodiesterase. Am J Physiol Cell Physiol 296:C1428-39 (2009). PubMed: 19357238
• Liu X  et al. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics 6:131-9 (2009). WB ; Human . PubMed: 19487542
• Hirano M  et al. Transcriptomic analysis of rat brain tissue following gamma knife surgery: early and distinct bilateral effects in the un-irradiated striatum. Mol Cells 27:263-8 (2009). WB ; Rat . PubMed: 19277511
• Sharkey D  et al. Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep. Hypertension 53:925-31 (2009). PubMed: 19414648
• Sharifi N  et al. Effects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer. Clin Cancer Res 14:6073-80 (2008). WB ; Human . PubMed: 18829485
• Gottipati S & Cammarata PR Mitochondrial superoxide dismutase activation with 17 beta-estradiol-treated human lens epithelial cells. Mol Vis 14:898-905 (2008). WB ; Human . PubMed: 18490963
• Yeung AT  et al. One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res 68:7579-86 (2008). PubMed: 18794146
• Bagnyukova TV  et al. Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet. Brain Res 1237:44-51 (2008). WB ; Rat . PubMed: 18694737
• Sartório CL  et al. Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. Hypertension 50:919-25 (2007). PubMed: 17846350
• Montilla SI  et al. Heat stress causes oxidative stress but not inflammatory signaling in porcine skeletal muscle. Temperature (Austin) 1:42-50 (0). PubMed: 27583280
• Kalash R  et al. Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice. In Vivo 28:147-71 (0). PubMed: 24632969
• Ren J  et al. Quantitative Proteomics of Sleep-Deprived Mouse Brains Reveals Global Changes in Mitochondrial Proteins. PLoS One 11:e0163500 (0). WB . PubMed: 27684481