Anti-SOD2/MnSOD antibody (ab13533)
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ab13533 has been referenced in 112 publications.
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- Jeong BY et al. Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury. PLoS One 13:e0191034 (2018). PubMed: 29329317
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- Shi Z et al. Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction. Biomed Res Int 2018:2708491 (2018). PubMed: 29765980
- Rabelo-Santos SH et al. Strong SOD2 expression and HPV-16/18 positivity are independent events in cervical cancer. Oncotarget 9:21630-21640 (2018). PubMed: 29774090
- Zhao D et al. Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice. Oxid Med Cell Longev 2018:4079041 (2018). PubMed: 29849892
- Zeng N et al. Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. Exp Gerontol 110:23-34 (2018). WB . PubMed: 29751091
- Zhao XL & Yu CZ Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway. Chem Biol Interact 290:57-63 (2018). WB ; Human . PubMed: 29800573
- Stancic A et al. A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection. Comp Biochem Physiol B Biochem Mol Biol 219-220:1-9 (2018). WB . PubMed: 29501789
- Li Y et al. A chlorogenic acid-phospholipid complex ameliorates post-myocardial infarction inflammatory response mediated by mitochondrial reactive oxygen species in SAMP8 mice. Pharmacol Res 130:110-122 (2018). WB . PubMed: 29408518
- Liu S et al. GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice. Biochim Biophys Acta Mol Basis Dis N/A:N/A (2018). PubMed: 30006154
- Zheng J et al. Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats. Front Neurosci 12:414 (2018). PubMed: 29970985
- Ganesan S et al. Prolonged environment-induced hyperthermia alters autophagy in oxidative skeletal muscle in Sus scrofa. J Therm Biol 74:160-169 (2018). PubMed: 29801622
- Pashkovskaia N et al. Mitochondrial ROS direct the differentiation of murine pluripotent P19 cells. Stem Cell Res 30:180-191 (2018). PubMed: 29957443
- Padrão AI et al. Exercise training protects against cancer-induced cardiac remodeling in an animal model of urothelial carcinoma. Arch Biochem Biophys 645:12-18 (2018). WB ; Rat . PubMed: 29548774
- Wang H et al. AMPKa2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction. Free Radic Biol Med 121:202-214 (2018). PubMed: 29753072
- Szelechowski M et al. Metabolic Reprogramming in Amyotrophic Lateral Sclerosis. Sci Rep 8:3953 (2018). PubMed: 29500423
- Wang Q et al. Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway. Int J Mol Med 41:1887-1898 (2018). PubMed: 29393371
- Yang Y et al. Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress-Mediated Atrial Remodeling in Alloxan-Induced Diabetes Mellitus Rabbits. J Am Heart Assoc 7:N/A (2018). PubMed: 29720500
- Ma J et al. Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway. Free Radic Biol Med 129:492-503 (2018). PubMed: 30342186
- Jing R et al. A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep 25:1469-1484.e5 (2018). PubMed: 30404003
- Li Z et al. TGF-ß induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure. Aging (Albany NY) 10:3474-3485 (2018). PubMed: 30482886
- Hancock M et al. Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:N/A (2018). PubMed: 30589411
- Banu SK et al. Editor's Highlight: Exposure to CrVI during Early Pregnancy Increases Oxidative Stress and Disrupts the Expression of Antioxidant Proteins in Placental Compartments. Toxicol Sci 155:497-511 (2017). PubMed: 28077780
- Li XZ et al. Astragaloside IV Prevents Cardiac Remodeling in the Apolipoprotein E-Deficient Mice by Regulating Cardiac Homeostasis and Oxidative Stress. Cell Physiol Biochem 44:2422-2438 (2017). PubMed: 29268252
- Volodina O et al. Short-term heat stress alters redox balance in porcine skeletal muscle. Physiol Rep 5:N/A (2017). PubMed: 28455453
- Liu JL et al. A single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1. Sci Rep 7:859 (2017). WB . PubMed: 28404998
- Yu EPK et al. Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness. Arterioscler Thromb Vasc Biol 37:2322-2332 (2017). WB ; Human . PubMed: 28970293
- Dunham J et al. Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey. PLoS One 12:e0188013 (2017). ICC/IF ; Monkey . PubMed: 29136024
- Katare PB et al. Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats. Front Immunol 8:719 (2017). PubMed: 28690610
- Zhang W et al. Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction. Oxid Med Cell Longev 2017:4082102 (2017). PubMed: 29209448
- Karwaciak I et al. TLR2 activation induces antioxidant defence in human monocyte-macrophage cell line models. Oncotarget 8:54243-54264 (2017). PubMed: 28903338
- Buck E et al. Comparison of Sirtuin 3 Levels in ALS and Huntington's Disease-Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models. Front Mol Neurosci 10:156 (2017). WB . PubMed: 28603486
- Bodega G et al. The Antioxidant Machinery of Young and Senescent Human Umbilical Vein Endothelial Cells and Their Microvesicles. Oxid Med Cell Longev 2017:7094781 (2017). WB ; Human . PubMed: 28642812
- Azimzadeh O et al. A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers. Oncotarget 8:9067-9078 (2017). WB . PubMed: 27391067
- Chavan H et al. Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response. Oxid Med Cell Longev 2017:9251303 (2017). WB ; Human . PubMed: 28163822
- Biswal MR et al. Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD. Invest Ophthalmol Vis Sci 58:1237-1245 (2017). WB ; Mouse . PubMed: 28241311
- Martinez L et al. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer 16:559 (2016). WB . PubMed: 27473585
- Carlson RI et al. Development and application of an antibody-based protein microarray to assess physiological stress in grizzly bears (Ursus arctos). Conserv Physiol 4:cow001 (2016). Other species . PubMed: 27293753
- Greco T et al. Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity. J Cereb Blood Flow Metab 36:1603-13 (2016). PubMed: 26661201
- Kim J et al. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1). Mol Neurodegener 11:55 (2016). WB ; Human . PubMed: 27456084
- Lee WH et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. Elife 5:N/A (2016). WB ; Mouse . PubMed: 27863209
- Zhang X et al. PGC-1a/ERRa-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase ß. Antioxid Redox Signal 24:312-28 (2016). PubMed: 26421366
- Jian Z et al. CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability. EMBO Mol Med 8:813-29 (2016). PubMed: 27286733
- Wang R et al. Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner. Aging (Albany NY) 8:1184-200 (2016). WB . PubMed: 27221200
- Mot AI et al. Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture. Int J Biochem Cell Biol 79:128-138 (2016). PubMed: 27590850
- Tweedie D et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. PLoS One 11:e0156493 (2016). PubMed: 27254111
- Safdar A et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle 6:7 (2016). WB . PubMed: 26834962
- Nguyen TT et al. Scavengers of reactive ?-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7. Aging (Albany NY) 8:1759-80 (2016). WB . PubMed: 27514077
- Ding Y et al. Absence of AMPKa2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts. Int J Biochem Cell Biol 71:72-80 (2016). PubMed: 26718972
- Muralimanoharan S et al. Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model. Autophagy 12:752-69 (2016). PubMed: 26986453
- Chen WM et al. Hepatoprotective effect of resveratrol against ethanol-induced oxidative stress through induction of superoxide dismutase in vivo and in vitro. Exp Ther Med 11:1231-1238 (2016). PubMed: 27073428
- Zhang J et al. The protective effects of human umbilical cord mesenchymal stem cells on damaged ovarian function: A comparative study. Biosci Trends 10:265-76 (2016). PubMed: 27464625
- Fisher-Wellman KH et al. A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice. Diabetes 65:3249-3261 (2016). PubMed: 27495226
- Lauritzen KH et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging 48:34-47 (2016). PubMed: 27639119
- Saha S et al. Mangiferin attenuates oxidative stress induced renal cell damage through activation of PI3K induced Akt and Nrf-2 mediated signaling pathways. Biochem Biophys Rep 5:313-327 (2016). PubMed: 28955838
- Ristic AJ et al. Hippocampal antioxidative system in mesial temporal lobe epilepsy. Epilepsia 56:789-99 (2015). PubMed: 25864570
- Zhu YW et al. Effect of dietary manganese on antioxidant status and expression levels of heat-shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures. Br J Nutr 114:1965-74 (2015). PubMed: 26435464
- Santi A et al. Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth. Biochim Biophys Acta 1853:3211-23 (2015). PubMed: 26384873
- Lauritzen KH et al. Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. Am J Physiol Heart Circ Physiol 309:H434-49 (2015). PubMed: 26055793
- Macanovic B et al. Correlation between sperm parameters and protein expression of antioxidative defense enzymes in seminal plasma: a pilot study. Dis Markers 2015:436236 (2015). PubMed: 25691806
- Xiong W et al. NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage. J Clin Invest 125:1433-45 (2015). IHC-Fr ; Mouse . PubMed: 25798616
- Moghimi E et al. Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral Sclerosis. PLoS One 10:e0126355 (2015). WB ; Mouse . PubMed: 26020962
- Wang P et al. Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer. Oncotarget 6:21148-58 (2015). Human . PubMed: 26020803
- Cherry AD et al. Peroxisome proliferator-activated receptor ? co-activator 1-a as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis. J Biol Chem 289:41-52 (2014). WB ; Mouse . PubMed: 24253037
- Salisbury TB et al. Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells. Biochem Pharmacol 91:390-9 (2014). PubMed: 24971714
- Fiesel FC et al. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci 127:3488-504 (2014). PubMed: 24928900
- Berhane H et al. Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice. Radiat Res 181:76-89 (2014). PubMed: 24397476
- Xiang M et al. Interferon regulatory factor 8 protects against cerebral ischaemic-reperfusion injury. J Neurochem 129:988-1001 (2014). PubMed: 24528256
- Morten KJ et al. Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts. J Pathol 229:755-64 (2013). WB . PubMed: 23303559
- Zhou L et al. The role of RING box protein 1 in mouse oocyte meiotic maturation. PLoS One 8:e68964 (2013). PubMed: 23874827
- Gammon L et al. Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism. PLoS One 8:e62493 (2013). WB . PubMed: 23638097
- Koga K et al. Macrophage migration inhibitory factor antagonizes pressure overload-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol 304:H282-93 (2013). WB ; Mouse . PubMed: 23144312
- Losón OC et al. Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell 24:659-67 (2013). WB ; Human . PubMed: 23283981
- Banduseela VC et al. Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle. Physiol Genomics 45:477-86 (2013). PubMed: 23572537
- Raju I et al. FoxO3a Serves as a Biomarker of Oxidative Stress in Human Lens Epithelial Cells under Conditions of Hyperglycemia. PLoS One 8:e67126 (2013). PubMed: 23805295
- Gill T & Levine AD Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. J Biol Chem 288:26246-55 (2013). PubMed: 23880762
- Pereira L et al. Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. EMBO Mol Med 5:1759-74 (2013). WB ; Human . PubMed: 24115572
- Zhu WJ et al. Amelioration of cardio-renal injury with aging in dahl salt-sensitive rats by H2-enriched electrolyzed water. Med Gas Res 3:26 (2013). WB ; Rat . PubMed: 24289332
- Kang C & Ji LL Muscle immobilization and remobilization downregulates PGC-1a signaling and the mitochondrial biogenesis pathway. J Appl Physiol (1985) 115:1618-25 (2013). WB ; Mouse . PubMed: 23970536
- Pohjoismäki JL et al. Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response. Nucleic Acids Res 40:6595-607 (2012). WB ; Rat . PubMed: 22508755
- Gilbert JS et al. Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. Hypertension 60:1545-51 (2012). PubMed: 23090773
- Mahne S et al. Environmentally persistent free radicals decrease cardiac function and increase pulmonary artery pressure. Am J Physiol Heart Circ Physiol 303:H1135-42 (2012). PubMed: 22942180
- Woolston CM et al. The prognostic and predictive power of redox protein expression for anthracycline-based chemotherapy response in locally advanced breast cancer. Mod Pathol 25:1106-16 (2012). IHC . PubMed: 22481283
- Yang Y et al. A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer. Cancer Genet 205:377-90 (2012). PubMed: 22867999
- Aare S et al. Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model. Physiol Genomics 44:865-77 (2012). PubMed: 22851759
- Powell KA et al. Mitochondrial localization and ocular expression of mutant Opa3 in a mouse model of 3-methylglutaconicaciduria type III. Invest Ophthalmol Vis Sci 52:4369-80 (2011). PubMed: 21613372
- Narayanan A et al. Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection. PLoS One 6:e20354 (2011). WB . PubMed: 21655261
- Chan NC et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20:1726-37 (2011). WB ; Human . PubMed: 21296869
- Bewley MA et al. Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae. Mol Cell Proteomics 10:M111.008193 (2011). WB ; Human . PubMed: 21474794
- Herring A et al. Exercise during pregnancy mitigates Alzheimer-like pathology in mouse offspring. FASEB J : (2011). Mouse . PubMed: 21948247
- Szego EM et al. Estrogen regulates cytoskeletal flexibility, cellular metabolism and synaptic proteins: A proteomic study. Psychoneuroendocrinology 35:807-19 (2010). WB, IHC-FoFr ; Mouse . PubMed: 20005634
- Bigi A et al. Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively. Glycobiology 20:148-57 (2010). WB ; African green monkey . PubMed: 19797320
- Yang Y et al. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet 196:45-55 (2010). PubMed: 19963135
- Safdar A et al. Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults. PLoS One 5:e10778 (2010). WB, IP . PubMed: 20520725
- Ahmad M et al. Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD. Am J Physiol Heart Circ Physiol 297:H1453-61 (2009). PubMed: 19666846
- Ghosh R et al. Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development. Transl Oncol 2:65-72 (2009). IHC-P ; Rat . PubMed: 19412421
- Zandi F et al. Proteomics analysis of BHK-21 cells infected with a fixed strain of rabies virus. Proteomics 9:2399-407 (2009). WB . PubMed: 19322775
- Azarashvili T et al. Ca2+-dependent permeability transition regulation in rat brain mitochondria by 2',3'-cyclic nucleotides and 2',3'-cyclic nucleotide 3'-phosphodiesterase. Am J Physiol Cell Physiol 296:C1428-39 (2009). PubMed: 19357238
- Liu X et al. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics 6:131-9 (2009). WB ; Human . PubMed: 19487542
- Hirano M et al. Transcriptomic analysis of rat brain tissue following gamma knife surgery: early and distinct bilateral effects in the un-irradiated striatum. Mol Cells 27:263-8 (2009). WB ; Rat . PubMed: 19277511
- Sharkey D et al. Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep. Hypertension 53:925-31 (2009). PubMed: 19414648
- Sharifi N et al. Effects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer. Clin Cancer Res 14:6073-80 (2008). WB ; Human . PubMed: 18829485
- Gottipati S & Cammarata PR Mitochondrial superoxide dismutase activation with 17 beta-estradiol-treated human lens epithelial cells. Mol Vis 14:898-905 (2008). WB ; Human . PubMed: 18490963
- Yeung AT et al. One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res 68:7579-86 (2008). PubMed: 18794146
- Bagnyukova TV et al. Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet. Brain Res 1237:44-51 (2008). WB ; Rat . PubMed: 18694737
- Sartório CL et al. Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. Hypertension 50:919-25 (2007). PubMed: 17846350
- Montilla SI et al. Heat stress causes oxidative stress but not inflammatory signaling in porcine skeletal muscle. Temperature (Austin) 1:42-50 (0). PubMed: 27583280
- Kalash R et al. Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice. In Vivo 28:147-71 (0). PubMed: 24632969
- Ren J et al. Quantitative Proteomics of Sleep-Deprived Mouse Brains Reveals Global Changes in Mitochondrial Proteins. PLoS One 11:e0163500 (0). WB . PubMed: 27684481