Anti-SOD2/MnSOD antibody (ab13534)

Rabbit polyclonal SOD2/MnSOD antibody. Validated in WB, IP, ELISA, IHC, ICC/IF and tested in Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Hamster, Cow, Dog, Human, Pig and more.

Publishing research using ab13534? Please let us know so that we can cite the reference in this datasheet.

ab13534 has been referenced in 54 publications.

  • Liu L  et al. The antagonistic effect of tamoxifen against d-galactosamine/lipopolysaccharide-induced acute liver failure is associated with reactivation of hepatic nuclear factor-?B. Immunopharmacol Immunotoxicol N/A:1-7 (2019). PubMed: 30721100
  • Yamada M  et al. p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle. FASEB J N/A:fj201900133R (2019). PubMed: 30913396
  • Rezzani R  et al. A carnosine analog with therapeutic potentials in the treatment of disorders related to oxidative stress. PLoS One 14:e0215170 (2019). PubMed: 30964920
  • Larsen S  et al. Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. Physiol Rep 6:e13793 (2018). PubMed: 30221830
  • Zhang X & Cai Y Effects of Ginkgo biloba leaf extract, shenmai and matrine on a human embryonic lung fibroblast fibrosis model. Exp Ther Med 16:4289-4295 (2018). PubMed: 30344702
  • Lee VS  et al. Effects of FOXM1 inhibition and ionizing radiation on melanoma cells. Oncol Lett 16:6822-6830 (2018). PubMed: 30405826
  • Wen L  et al. Pyrroloquinoline quinone induces chondrosarcoma cell apoptosis by increasing intracellular reactive oxygen species. Mol Med Rep 17:7184-7190 (2018). PubMed: 29568949
  • Yu T  et al. Ligustrazine protects chondrocyte against IL-1ß induced injury by regulation of SOX9/NF-?B signaling pathway. J Cell Biochem 119:7419-7430 (2018). PubMed: 29806884
  • Yagil C  et al. A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model. Dis Model Mech 11:N/A (2018). PubMed: 30361421
  • Wilson RJ  et al. Voluntary running protects against neuromuscular dysfunction following hindlimb ischemia-reperfusion in mice. J Appl Physiol (1985) N/A:N/A (2018). PubMed: 30433863
  • Bhattacharjee B  et al. Aqueous bark extract of Terminalia arjuna protects against cadmium-induced hepatic and cardiac injuries in male Wistar rats through antioxidative mechanisms. Food Chem Toxicol 124:249-264 (2018). PubMed: 30529122
  • Xia S  et al. Abnormal expression of microRNA-575 leads to missed abortion through regulating apoptosis and angiogenesis. Exp Ther Med 14:3993-4000 (2017). WB ; Human . PubMed: 29104621
  • Takakura K  et al. Cordyceps militaris improves the survival of Dahl salt-sensitive hypertensive rats possibly via influences of mitochondria and autophagy functions. Heliyon 3:e00462 (2017). WB ; Rat . PubMed: 29264419
  • Assiri MA  et al. Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation. Alcohol Clin Exp Res 41:1705-1714 (2017). PubMed: 28804911
  • Jiang YF  et al. Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging. Sci Rep 7:45474 (2017). WB . PubMed: 28358017
  • Shanmugam G  et al. Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium. Redox Biol 12:937-945 (2017). WB ; Mouse . PubMed: 28482326
  • Kaczor JJ  et al. Higher oxidative stress in skeletal muscle of McArdle disease patients. Mol Genet Metab Rep 12:69-75 (2017). WB ; Human . PubMed: 28649515
  • Shanmugam G  et al. A biphasic effect of TNF-a in regulation of the Keap1/Nrf2 pathway in cardiomyocytes. Redox Biol 9:77-89 (2016). PubMed: 27423013
  • Perkins AT  et al. Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors. Proc Natl Acad Sci U S A 113:E6823-E6830 (2016). WB . PubMed: 27791141
  • Guan Y  et al. Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1a-SIRT3 signaling pathway. Int J Mol Med 37:1229-38 (2016). WB . PubMed: 27049825
  • Blanco S  et al. Stem cell function and stress response are controlled by protein synthesis. Nature 534:335-40 (2016). WB ; Mouse . PubMed: 27306184
  • Jacobs RA  et al. Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66 (2016). PubMed: 26339730
  • Nilsson MI  et al. Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease. Free Radic Biol Med 87:98-112 (2015). WB . PubMed: 26001726
  • Nojima Y  et al. Superoxide dismutases, SOD1 and SOD2, play a distinct role in the fat body during pupation in silkworm Bombyx mori. PLoS One 10:e0116007 (2015). WB . PubMed: 25714339
  • Liu G  et al. Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene. Am J Physiol Cell Physiol 309:C169-78 (2015). PubMed: 25948732
  • Kinugasa H  et al. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene 34:5229-39 (2015). WB, IF . PubMed: 25659582
  • Qu Z  et al. NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells. J Neuroinflammation 11:17 (2014). Mouse . PubMed: 24472655
  • Nilsson MI  et al. Redox State and Mitochondrial Respiratory Chain Function in Skeletal Muscle of LGMD2A Patients. PLoS One 9:e102549 (2014). WB ; Human . PubMed: 25079074
  • Ramiro-Diaz JM  et al. Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle. Am J Physiol Cell Physiol 307:C928-38 (2014). PubMed: 25163518
  • Wong HK  et al. De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease. Hum Mol Genet 22:3077-92 (2013). PubMed: 23585551
  • Samjoo IA  et al. The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men. Nutr Diabetes 3:e88 (2013). PubMed: 24042701
  • Crane JD  et al. Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. PLoS One 8:e81879 (2013). WB ; Mouse . PubMed: 24324727
  • Lanoix D  et al. Melatonin: The watchdog of villous trophoblast homeostasis against hypoxia/reoxygenation-induced oxidative stress and apoptosis. Mol Cell Endocrinol 381:35-45 (2013). WB ; Human . PubMed: 23886990
  • Hüttemann M  et al. Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy. Mitochondrion 12:294-304 (2012). PubMed: 22119795
  • Muthusamy VR  et al. Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium. Free Radic Biol Med 52:366-76 (2012). PubMed: 22051043
  • Rubovitch V  et al. A mouse model of blast-induced mild traumatic brain injury. Exp Neurol 232:280-9 (2011). IHC-P ; Mouse . PubMed: 21946269
  • Gigante AD  et al. Decreased mRNA expression of uncoupling protein 2, a mitochondrial proton transporter, in post-mortem prefrontal cortex from patients with bipolar disorder and schizophrenia. Neurosci Lett 505:47-51 (2011). WB . PubMed: 22001364
  • Lee I  et al. A suggested role for mitochondria in Noonan syndrome. Biochim Biophys Acta 1802:275-83 (2010). PubMed: 19835954
  • Xu L  et al. Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia. Glia 58:1042-9 (2010). IHC-Fr ; Rat . PubMed: 20235222
  • Tang D  et al. Endogenous HMGB1 regulates autophagy. J Cell Biol 190:881-92 (2010). WB ; Human . PubMed: 20819940
  • Kim J  et al. Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease. Hum Mol Genet 19:3919-35 (2010). ICC/IF ; Human . PubMed: 20660112
  • Patel BP  et al. Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. PLoS One 5:e9386 (2010). WB . PubMed: 20195368
  • Uittenbogaard M  et al. The neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass. ASN Neuro 2:e00034 (2010). PubMed: 20517466
  • Kathleen Baxter K  et al. The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro 1: (2009). ICC/IF ; Rat . PubMed: 19743964
  • Ying YL & Balaban CD Regional distribution of manganese superoxide dismutase 2 (Mn SOD2) expression in rodent and primate spiral ganglion cells. Hear Res 253:116-24 (2009). PubMed: 19376215
  • Lopez IA  et al. Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air). BMC Neurosci 10:53 (2009). ICC/IF ; Rat . PubMed: 19580685
  • Boyd RS  et al. Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma. Mol Cell Proteomics 8:1501-15 (2009). WB ; Human . PubMed: 19346216
  • Harada M  et al. Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation. Hepatology 47:2026-35 (2008). WB ; Human . PubMed: 18454506
  • Jones CI  et al. Endothelial cell respiration is affected by the oxygen tension during shear exposure: role of mitochondrial peroxynitrite. Am J Physiol Cell Physiol 295:C180-91 (2008). PubMed: 18480296
  • Tokarska-Schlattner M  et al. The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration. J Biol Chem 283:26198-207 (2008). WB, IP ; Rat . PubMed: 18635542
  • Magwere T  et al. Manipulation of oxidative stress to induce cell death in Ewing's sarcoma family of tumours. Eur J Cancer 44:2276-87 (2008). WB ; Human . PubMed: 18656345
  • Deng FY  et al. Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density. Proteomics 8:4259-72 (2008). PubMed: 18924182
  • Weinberger M  et al. DNA replication stress is a determinant of chronological lifespan in budding yeast. PLoS One 2:e748 (2007). WB ; Mouse . PubMed: 17710147
  • Saha RN & Pahan K Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radic Biol Med 42:1866-78 (2007). PubMed: 17512466

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