Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)](https://www.abcam.com/ps/products/242/ab242007/Images/ab242007-333096-anti-sodium-iodide-symporter-antibody-fp5-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)")
Key features and details
- Mouse monoclonal [FP5] to Sodium Iodide Symporter
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG1
Overview
-
Product name
Anti-Sodium Iodide Symporter antibody [FP5]
See all Sodium Iodide Symporter primary antibodies -
Description
Mouse monoclonal [FP5] to Sodium Iodide Symporter -
Host species
Mouse -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P MouseWB Human
-
Immunogen
Fusion protein corresponding to Human Sodium Iodide Symporter aa 450 to the C-terminus. NP_000444.1
Database link: Q92911 -
Positive control
- IHC-P: Mouse thyroid and trachea tissue. WB: Human thyroid lysate.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
Purified from TCS. -
Clonality
Monoclonal -
Clone number
FP5 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
-
Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab242007 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Mouse
|
| WB |
Human
|
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/1000.
|
|
| WB |
1/1000. Predicted molecular weight: 68 kDa.
|
| Notes |
|---|
|
IHC-P
1/1000. |
|
WB
1/1000. Predicted molecular weight: 68 kDa. |
Target
-
Function
Mediates iodide uptake in the thyroid gland. -
Tissue specificity
Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. -
Involvement in disease
Thyroid dyshormonogenesis 1 -
Sequence similarities
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 6528 Human
- Entrez Gene: 114479 Mouse
- Omim: 601843 Human
- SwissProt: Q92911 Human
- SwissProt: Q99PN0 Mouse
- Unigene: 584804 Human
- Unigene: 172923 Mouse
-
Alternative names
- Na(+)/I(-) cotransporter antibody
- Na(+)/I(-) symporter antibody
- Na+/I- cotransporter antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.
Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.
-
![Western blot - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)](https://www.abcam.com/ps/products/242/ab242007/Images/ab242007-333095-anti-sodium-iodide-symporter-antibody-fp5-western-blot.jpg)
Western blot - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)Anti-Sodium Iodide Symporter antibody [FP5] (ab242007) at 1/1000 dilution + Human thyroid lysate
Predicted band size: 68 kDa -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)](https://www.abcam.com/ps/products/242/ab242007/Images/ab242007-333094-anti-sodium-iodide-symporter-antibody-fp5-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)Formalin-fixed, paraffin-embedded mouse trachea tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.
Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)](https://www.abcam.com/ps/products/242/ab242007/Images/ab242007-333093-anti-sodium-iodide-symporter-antibody-fp5-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.
Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)](https://www.abcam.com/ps/products/242/ab242007/Images/ab242007-333092-anti-sodium-iodide-symporter-antibody-fp5-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.
Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab242007 has not yet been referenced specifically in any publications.
