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    sodium-iodide-symporter-antibody-fp5-ab242007.pdf

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Signal Transduction Metabolism Plasma Membrane Channels
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Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
  • Western blot - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

Key features and details

  • Mouse monoclonal [FP5] to Sodium Iodide Symporter
  • Suitable for: IHC-P, WB
  • Reacts with: Mouse, Human
  • Isotype: IgG1

You may also be interested in

Secondary
Product image
Goat Anti-Mouse IgG H&L (HRP) (ab205719)

View more associated products

Overview

  • Product name

    Anti-Sodium Iodide Symporter antibody [FP5]
    See all Sodium Iodide Symporter primary antibodies
  • Description

    Mouse monoclonal [FP5] to Sodium Iodide Symporter
  • Host species

    Mouse
  • Tested Applications & Species

    Application Species
    IHC-P
    Mouse
    WB
    Human
    See all applications and species data
  • Immunogen

    Fusion protein corresponding to Human Sodium Iodide Symporter aa 450 to the C-terminus. NP_000444.1
    Database link: Q92911

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • IHC-P: Mouse thyroid and trachea tissue. WB: Human thyroid lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purified from TCS.
  • Clonality

    Monoclonal
  • Clone number

    FP5
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

    • Signal Transduction
    • Metabolism
    • Plasma Membrane
    • Channels
    • Signal Transduction
    • Metabolism
    • Vitamins / Minerals
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Hormone biosynthesis
    • Metabolism
    • Pathways and Processes
    • Cofactors, Vitamins / minerals
    • Vitamins / minerals
    • Metabolism
    • Pathways and Processes
    • Endocrine metabolism
    • Hormone biosynthesis

Associated products

  • Compatible Secondaries

    • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
    • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab242007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-P
Mouse
WB
Human
Application Abreviews Notes
IHC-P
1/1000.
WB
1/1000. Predicted molecular weight: 68 kDa.
Notes
IHC-P
1/1000.
WB
1/1000. Predicted molecular weight: 68 kDa.

Target

  • Function

    Mediates iodide uptake in the thyroid gland.
  • Tissue specificity

    Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
  • Involvement in disease

    Thyroid dyshormonogenesis 1
  • Sequence similarities

    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Cellular localization

    Membrane.
  • Target information above from: UniProt accession Q92911 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 6528 Human
    • Entrez Gene: 114479 Mouse
    • Omim: 601843 Human
    • SwissProt: Q92911 Human
    • SwissProt: Q99PN0 Mouse
    • Unigene: 584804 Human
    • Unigene: 172923 Mouse
    • Alternative names

      • Na(+)/I(-) cotransporter antibody
      • Na(+)/I(-) symporter antibody
      • Na+/I- cotransporter antibody
      • Na+/I-symporter antibody
      • NIS antibody
      • SC5A5_HUMAN antibody
      • Slc5a5 antibody
      • sodium iodide symporter antibody
      • Sodium-iodide symporter antibody
      • Sodium/iodide cotransporter antibody
      • Solute carrier family 5 (sodium iodide symporter) member 5 antibody
      • solute carrier family 5 (sodium/iodide cotransporter), member 5 antibody
      • Solute carrier family 5 member 5 antibody
      • TDH1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

      Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.

      Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.

    • Western blot - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Western blot - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Anti-Sodium Iodide Symporter antibody [FP5] (ab242007) at 1/1000 dilution + Human thyroid lysate

      Predicted band size: 68 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

      Formalin-fixed, paraffin-embedded mouse trachea tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.

      Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

      Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.

      Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Iodide Symporter antibody [FP5] (ab242007)

      Formalin-fixed, paraffin-embedded mouse thyroid tissue stained for Sodium Iodide Symporter with ab242007 at a 1/1000 dilution for 1 hr at RT in immunohistochemical analysis. Fixation: 10% Formalin Solution for 12-24 hours at RT.

      Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µL for 5 minutes at RT.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab242007? Please let us know so that we can cite the reference in this datasheet.

    ab242007 has not yet been referenced specifically in any publications.

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