Anti-Sodium Iodide Symporter antibody - N-terminal (ab199410)
Key features and details
- Rabbit polyclonal to Sodium Iodide Symporter - N-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Sodium Iodide Symporter antibody - N-terminal
See all Sodium Iodide Symporter primary antibodies -
Description
Rabbit polyclonal to Sodium Iodide Symporter - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human Sodium Iodide Symporter (N terminal). The exact sequence is proprietary. NCBI Accession No. NP_000444
Database link: Q92911 -
Positive control
- Human colon and ovarian cancer tissue lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab199410 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/450 - 1/2000. Predicted molecular weight: 69 kDa.
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Notes |
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WB
1/450 - 1/2000. Predicted molecular weight: 69 kDa. |
Target
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Function
Mediates iodide uptake in the thyroid gland. -
Tissue specificity
Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. -
Involvement in disease
Thyroid dyshormonogenesis 1 -
Sequence similarities
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 6528 Human
- Omim: 601843 Human
- SwissProt: Q92911 Human
- Unigene: 584804 Human
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Alternative names
- Na(+)/I(-) cotransporter antibody
- Na(+)/I(-) symporter antibody
- Na+/I- cotransporter antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab199410 has been referenced in 2 publications.
- Riley A et al. A novel microfluidic device capable of maintaining functional thyroid carcinoma specimens ex vivo provides a new drug screening platform. BMC Cancer 19:259 (2019). PubMed: 30902086
- Riley AS et al. The effect of radioiodine treatment on the diseased thyroid gland. Int J Radiat Biol 95:1718-1727 (2019). PubMed: 31486712