Overview

  • Product name

    Anti-Sodium Iodide Symporter antibody - N-terminal
    See all Sodium Iodide Symporter primary antibodies
  • Description

    Rabbit polyclonal to Sodium Iodide Symporter - N-terminal
  • Host species

    Rabbit
  • Specificity

    ab199410 detects endogenous level of total Sodium Iodide Symporter protein.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Sodium Iodide Symporter (N terminal). The exact sequence is proprietary. NCBI Accession No. NP_000444
    Database link: Q92911

  • Positive control

    • Human colon and ovarian cancer tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab199410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/450 - 1/2000. Predicted molecular weight: 69 kDa.

Target

  • Function

    Mediates iodide uptake in the thyroid gland.
  • Tissue specificity

    Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
  • Involvement in disease

    Thyroid dyshormonogenesis 1
  • Sequence similarities

    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Na(+)/I(-) cotransporter antibody
    • Na(+)/I(-) symporter antibody
    • Na+/I- cotransporter antibody
    • Na+/I-symporter antibody
    • NIS antibody
    • SC5A5_HUMAN antibody
    • Slc5a5 antibody
    • sodium iodide symporter antibody
    • Sodium-iodide symporter antibody
    • Sodium/iodide cotransporter antibody
    • Solute carrier family 5 (sodium iodide symporter) member 5 antibody
    • solute carrier family 5 (sodium/iodide cotransporter), member 5 antibody
    • Solute carrier family 5 member 5 antibody
    • TDH1 antibody
    see all

Images

  • All lanes : Anti-Sodium Iodide Symporter antibody - N-terminal (ab199410) at 1/450 dilution

    Lane 1 : Human colon cancer lysate
    Lane 2 : Human ovarian cancer lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 69 kDa



    8%SDS-PAGE

References

This product has been referenced in:

  • Riley A  et al. A novel microfluidic device capable of maintaining functional thyroid carcinoma specimens ex vivo provides a new drug screening platform. BMC Cancer 19:259 (2019). Read more (PubMed: 30902086) »
See 1 Publication for this product

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