Product nameSodium nitroprusside, Vasodilator
DescriptionPotent vasodilator working through releasing NO spontaneously in blood.
- Nitroprusside sodium
Potent vasodilating effects in arterioles and venules. Breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate. Decreases the proliferation of vascular smooth muscle cells. Significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in DMSO to 201.37 mM and in water to 201.37 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145732 has not yet been referenced specifically in any publications.