• Product name
    Anti-Sodium/Hydrogen Exchanger 1/NHE-1 antibody
    See all Sodium/Hydrogen Exchanger 1/NHE-1 primary antibodies
  • Description
    Rabbit polyclonal to Sodium/Hydrogen Exchanger 1/NHE-1
  • Host species
  • Tested applications
    Suitable for: IHC-FoFr, WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Sodium/Hydrogen Exchanger 1/NHE-1 (C terminal).

  • Positive control
    • Kidney. Brain.
  • General notes

    Previously labelled as Sodium / Hydrogen Exchanger 1.



Our Abpromise guarantee covers the use of ab67313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration. PubMed: 21705333
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.


  • Function
    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Tissue specificity
    Kidney and intestine.
  • Sequence similarities
    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • amiloride-sensitive antibody
    • APNH antibody
    • APNH1 antibody
    • FLJ42224 antibody
    • Na Li countertransporter antibody
    • Na(+)/H(+) antiporter antibody
    • Na(+)/H(+) exchanger 1 antibody
    • Na+ H+ antiporter amiloride-sensitive antibody
    • Na+ H+ antiporter antibody
    • Na+ H+ exchanger 1 antibody
    • NHE-1 antibody
    • NHE1 antibody
    • OTTHUMP00000004468 antibody
    • SL9A1_HUMAN antibody
    • SLC9A1 antibody
    • Sodium / Hydrogen Exchanger 1 antibody
    • Sodium hydrogen exchanger 1 antibody
    • Sodium/hydrogen exchanger 1 antibody
    • solute carrier family 9 antibody
    • Solute carrier family 9 member 1 antibody
    • Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody
    • Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody
    • Solute carrier family 9 subfamily A member 1 antibody
    see all


  • Lane 1 : Anti-Sodium/Hydrogen Exchanger 1/NHE-1 antibody (ab67313) at 1 µg/ml
    Lane 2 : Anti-Sodium/Hydrogen Exchanger 1/NHE-1 antibody (ab67313) at 2 µg/ml

    All lanes : Rat kidney tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 91 kDa
    Observed band size: 91 kDa
    Additional bands at: 50 kDa, 70 kDa. We are unsure as to the identity of these extra bands.

  • ab67313 at 2.5 μg/ml staining of Sodium/Hydrogen Exchanger 1/NHE-1 in human brain tissue using IHC-P.

  • Immunofluorescence of Nhe-1 in Human Brain cells using ab67313 at 20 ug/ml.


This product has been referenced in:
  • Kao L  et al. Severe Neurologic Impairment in Mice with Targeted Disruption of the Electrogenic Sodium Bicarbonate Cotransporter NBCe2 (Slc4a5 Gene). J Biol Chem 286:32563-74 (2011). IHC-FoFr ; Mouse . Read more (PubMed: 21705333) »
  • Uray KS  et al. Sodium hydrogen exchanger as a mediator of hydrostatic edema-induced intestinal contractile dysfunction. Surgery 149:114-25 (2011). Read more (PubMed: 20553904) »
See all 2 Publications for this product

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