Key features and details
- Rabbit polyclonal to Sodium/Hydrogen Exchanger 3/NHE-3
- Suitable for: WB, IHC-Fr
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Sodium/Hydrogen Exchanger 3/NHE-3 antibody
See all Sodium/Hydrogen Exchanger 3/NHE-3 primary antibodies
DescriptionRabbit polyclonal to Sodium/Hydrogen Exchanger 3/NHE-3
Tested applicationsSuitable for: WB, IHC-Frmore details
Species reactivityReacts with: Human
Predicted to work with: Rat
Synthetic peptide corresponding to Human Sodium/Hydrogen Exchanger 3/NHE-3 (internal sequence).
Previously labelled as Sodium / Hydrogen Exchanger 3.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferConstituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab90630 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 93 kDa.|
|IHC-Fr||Use at an assay dependent concentration.|
FunctionInvolved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
modificationsPhosphorylated by PKA, which inhibits activity.
Cellular localizationMembrane. In intestinal epithelial cells, localizes to the ileal brush border.
- Information by UniProt
- MGC126718 antibody
- MGC126720 antibody
- Na(+)/H(+) exchanger 3 antibody
ab90630 has been referenced in 1 publication.
- Chen GS et al. Functional and molecular characterization of transmembrane intracellular pH regulators in human dental pulp stem cells. Arch Oral Biol 90:19-26 (2018). WB . PubMed: 29524788