Overview

  • Product name

    Anti-Sodium/Hydrogen Exchanger 3/NHE-3 antibody
    See all Sodium/Hydrogen Exchanger 3/NHE-3 primary antibodies
  • Description

    Rabbit polyclonal to Sodium/Hydrogen Exchanger 3/NHE-3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Frmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human Sodium/Hydrogen Exchanger 3/NHE-3 (internal sequence).

  • General notes

    Previously labelled as Sodium / Hydrogen Exchanger 3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab90630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 93 kDa.
IHC-Fr Use at an assay dependent concentration.

Target

  • Function

    Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
  • Sequence similarities

    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Post-translational
    modifications

    Phosphorylated by PKA, which inhibits activity.
  • Cellular localization

    Membrane. In intestinal epithelial cells, localizes to the ileal brush border.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC126718 antibody
    • MGC126720 antibody
    • Na(+)/H(+) exchanger 3 antibody
    • NHE 3 antibody
    • NHE-3 antibody
    • NHE3 antibody
    • SL9A3_HUMAN antibody
    • SLC9A 3 antibody
    • Slc9a3 antibody
    • Sodium / Hydrogen Exchanger 3 antibody
    • Sodium/hydrogen exchanger 3 antibody
    • Sodium/hydrogen exchanger, apical epithelial antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), member 3 antibody
    • Solute carrier family 9 member 3 antibody
    see all

References

This product has been referenced in:

  • Chen GS  et al. Functional and molecular characterization of transmembrane intracellular pH regulators in human dental pulp stem cells. Arch Oral Biol 90:19-26 (2018). WB . Read more (PubMed: 29524788) »
See 1 Publication for this product

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