Key features and details
- Rabbit polyclonal to Sodium/Hydrogen Exchanger 3/NHE-3
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-Sodium/Hydrogen Exchanger 3/NHE-3 antibody
See all Sodium/Hydrogen Exchanger 3/NHE-3 primary antibodies
DescriptionRabbit polyclonal to Sodium/Hydrogen Exchanger 3/NHE-3
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat
- Rat kidney tissue lysate.
Previously labelled as Sodium / Hydrogen Exchanger 3.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferConstituent: 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab95299 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 93 kDa).|
FunctionInvolved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
modificationsPhosphorylated by PKA, which inhibits activity.
Cellular localizationMembrane. In intestinal epithelial cells, localizes to the ileal brush border.
- Information by UniProt
- MGC126718 antibody
- MGC126720 antibody
- Na(+)/H(+) exchanger 3 antibody
ab95299 has been referenced in 3 publications.
- Tingskov SJ et al. Tamoxifen Decreases Lithium-Induced Natriuresis in Rats With Nephrogenic Diabetes Insipidus. Front Physiol 9:903 (2018). PubMed: 30050465
- Wang YY et al. SLC9A3 Protein Is Critical for Acrosomal Formation in Postmeiotic Male Germ Cells. Int J Mol Sci 19:N/A (2017). PubMed: 29286340
- Wang YY et al. Loss of SLC9A3 decreases CFTR protein and causes obstructed azoospermia in mice. PLoS Genet 13:e1006715 (2017). IHC-P ; Mouse . PubMed: 28384194