Overview

  • Product name
    Anti-Somatostatin Receptor 3 antibody
    See all Somatostatin Receptor 3 primary antibodies
  • Description
    Rabbit polyclonal to Somatostatin Receptor 3
  • Host species
    Rabbit
  • Specificity
    Ab28680 detects Somatostatin Receptor 3.
  • Tested applications
    Suitable for: IHC-P, WB, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-QERPPSRVA

    , corresponding to amino acids 385-393 of Human Somatostatin Receptor 3.

  • Positive control
    • Human pancreatic islands. HEK293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab28680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/2500.
WB 1/5000. Predicted molecular weight: 46 kDa.
ICC 1/5000.

Target

  • Function
    Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
  • Tissue specificity
    Brain, pituitary and pancreas.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Phosphorylated. Phosphorylation increases upon somatostatin binding.
  • Cellular localization
    Cell membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation.
  • Information by UniProt
  • Database links
  • Alternative names
    • OTTHUMP00000028737 antibody
    • Smstr 3 antibody
    • Smstr3 antibody
    • Somatostatin receptor subtype 3 antibody
    • Somatostatin receptor type 3 antibody
    • SS 3R antibody
    • SS-3-R antibody
    • SS3-R antibody
    • SS3R antibody
    • SSR 28 antibody
    • SSR-28 antibody
    • SSR28 antibody
    • SSR3_HUMAN antibody
    • Sst 3 antibody
    • Sst3 antibody
    • SSTR 3 antibody
    • SSTR3 antibody
    see all

Images

  • ab28680, at a dilution of 1/2500, staining Human pancreatic islands by Immunohistochemistry.

References

This product has been referenced in:
  • Kiviniemi A  et al. Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with (68)Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy. EJNMMI Res 5:25 (2015). IHC . Read more (PubMed: 25977882) »
  • Righi L  et al. Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases. Ann Oncol : (2009). IHC ; Human . Read more (PubMed: 19759190) »
See all 3 Publications for this product

Customer reviews and Q&As

Answer

Thank you for contacting us.

I am sorry to report that the blocking peptide for this antibody is not available.

I do hope that the suggestions whcih we spoke of help. Please do not hesitate to contact us if you need any more advice or information.

Free Rabbit monoclonal antibody with any purchase of a primary antibody, while stocks last! Quote “RABMAB-XBSMG” in your next primary antibody order. For more information, visit the following link: https://www.abcam.com/index.html?pageconfig=resource&rid=15447

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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