Overview

  • Product name

    Anti-Somatostatin Receptor 3/SSTR3 antibody [7H8E5]
    See all Somatostatin Receptor 3/SSTR3 primary antibodies
  • Description

    Mouse monoclonal [7H8E5] to Somatostatin Receptor 3/SSTR3
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human Somatostatin Receptor 3/SSTR3 aa 1-43. Recombinant fragment corresponding to extracellular domain of human Somatostatin Receptor 3/SSTR3 expressed in E coli
    Sequence:

    MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVS


    Database link: P32745

  • Positive control

    • Human Somatostatin Receptor 3/SSTR3 (AA: 1-43) recombinant protein; Human Somatostatin Receptor 3/SSTR3 (AA: 1-43) transfected HEK293 cell lysate; HeLA; PANC1; PC-12; SK N SH; U937 and HepG2 whole cell lysate (ab7900). HeLa cells.
  • General notes

     This product was previously labelled as Somatostatin Receptor 3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab201952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 46 kDa.
Flow Cyt 1/200 - 1/400.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
  • Tissue specificity

    Brain, pituitary and pancreas.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Phosphorylated. Phosphorylation increases upon somatostatin binding.
  • Cellular localization

    Cell membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation.
  • Information by UniProt
  • Database links

  • Alternative names

    • OTTHUMP00000028737 antibody
    • Smstr 3 antibody
    • Smstr3 antibody
    • Somatostatin receptor subtype 3 antibody
    • Somatostatin receptor type 3 antibody
    • SS 3R antibody
    • SS-3-R antibody
    • SS3-R antibody
    • SS3R antibody
    • SSR 28 antibody
    • SSR-28 antibody
    • SSR28 antibody
    • SSR3_HUMAN antibody
    • Sst 3 antibody
    • Sst3 antibody
    • SSTR 3 antibody
    • SSTR3 antibody
    see all

Images

  • Flow cytometric analysis of Hela cells labeling Smoatostatin Receptor 3 using ab 201952 at 1/200 dilution (green) and negative control (red).

  • All lanes : Anti-Somatostatin Receptor 3/SSTR3 antibody [7H8E5] (ab201952) at 1/500 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : PANC1 cell lysate
    Lane 3 : PC 12 cell lysate
    Lane 4 : SK N SH cell lysate
    Lane 5 : U937 cell lysate
    Lane 6 : HepG2 cell lysate

    Predicted band size: 46 kDa

  • All lanes : Anti-Somatostatin Receptor 3/SSTR3 antibody [7H8E5] (ab201952) at 1/500 dilution

    Lane 1 : HEK293 cell lysate
    Lane 2 : Human Somatostatin Receptor 3/SSTR3 (AA: 1-43) recombinant protein trasfected HEK293 cell lysate

    Predicted band size: 46 kDa

  • Anti-Somatostatin Receptor 3/SSTR3 antibody [7H8E5] (ab201952) at 1/500 dilution + Human Somatostatin Receptor 3/SSTR3 (AA: 1-43) recombinant protein

    Predicted band size: 46 kDa



    Expected MW is 30.2 kD

References

ab201952 has not yet been referenced specifically in any publications.

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