Anti-Somatostatin Receptor 3/SSTR3 antibody (ab28680)
Key features and details
- Rabbit polyclonal to Somatostatin Receptor 3/SSTR3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Somatostatin Receptor 3/SSTR3 antibody
See all Somatostatin Receptor 3/SSTR3 primary antibodies -
Description
Rabbit polyclonal to Somatostatin Receptor 3/SSTR3 -
Host species
Rabbit -
Specificity
Ab28680 detects Somatostatin Receptor 3/SSTR3.
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Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human Somatostatin Receptor 3/SSTR3 aa 385-393.
Sequence:C-QERPPSRVA
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Positive control
- Human pancreatic islands. HeLa lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab28680 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/2500.
|
Notes |
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IHC-P
1/2500. |
Target
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Function
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. -
Tissue specificity
Brain, pituitary and pancreas. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Post-translational
modificationsPhosphorylated. Phosphorylation increases upon somatostatin binding. -
Cellular localization
Cell membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation. - Information by UniProt
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Database links
- Entrez Gene: 6753 Human
- Omim: 182453 Human
- SwissProt: P32745 Human
- Unigene: 225995 Human
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Alternative names
- OTTHUMP00000028737 antibody
- Smstr 3 antibody
- Smstr3 antibody
see all
Datasheets and documents
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Datasheet download
References (3)
ab28680 has been referenced in 3 publications.
- Kiviniemi A et al. Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with (68)Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy. EJNMMI Res 5:25 (2015). IHC . PubMed: 25977882
- Righi L et al. Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases. Ann Oncol : (2009). IHC ; Human . PubMed: 19759190
- Volante M et al. Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphy. Mod Pathol 20:1172-82 (2007). PubMed: 17873898