Overview

  • Product name

    Anti-Somatostatin Receptor 3/SSTR3 antibody
    See all Somatostatin Receptor 3/SSTR3 primary antibodies
  • Description

    Rabbit polyclonal to Somatostatin Receptor 3/SSTR3
  • Host species

    Rabbit
  • Specificity

    Ab28680 detects Somatostatin Receptor 3/SSTR3.

  • Tested applications

    Suitable for: IHC-P, WB, ICCmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Somatostatin Receptor 3/SSTR3 aa 385-393.
    Sequence:

    C-QERPPSRVA

  • Positive control

    • Human pancreatic islands. HEK293 cell lysate.
  • General notes

     This product was previously labelled as Somatostatin Receptor 3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab28680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/2500.
WB 1/5000. Predicted molecular weight: 46 kDa.
ICC 1/5000.

Target

  • Function

    Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
  • Tissue specificity

    Brain, pituitary and pancreas.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Phosphorylated. Phosphorylation increases upon somatostatin binding.
  • Cellular localization

    Cell membrane. Internalized into endoplasmic vesicles upon somatostatin-stimulation.
  • Information by UniProt
  • Database links

  • Alternative names

    • OTTHUMP00000028737 antibody
    • Smstr 3 antibody
    • Smstr3 antibody
    • Somatostatin receptor subtype 3 antibody
    • Somatostatin receptor type 3 antibody
    • SS 3R antibody
    • SS-3-R antibody
    • SS3-R antibody
    • SS3R antibody
    • SSR 28 antibody
    • SSR-28 antibody
    • SSR28 antibody
    • SSR3_HUMAN antibody
    • Sst 3 antibody
    • Sst3 antibody
    • SSTR 3 antibody
    • SSTR3 antibody
    see all

Images

  • ab28680, at a dilution of 1/2500, staining Human pancreatic islands by Immunohistochemistry.

References

This product has been referenced in:

  • Kiviniemi A  et al. Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with (68)Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy. EJNMMI Res 5:25 (2015). IHC . Read more (PubMed: 25977882) »
  • Righi L  et al. Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases. Ann Oncol : (2009). IHC ; Human . Read more (PubMed: 19759190) »
See all 3 Publications for this product

Customer reviews and Q&As

Answer

Thank you for contacting us.

I am sorry to report that the blocking peptide for this antibody is not available.

I do hope that the suggestions whcih we spoke of help. Please do not hesitate to contact us if you need any more advice or information.

Free Rabbit monoclonal antibody with any purchase of a primary antibody, while stocks last! Quote “RABMAB-XBSMG” in your next primary antibody order. For more information, visit the following link: https://www.abcam.com/index.html?pageconfig=resource&rid=15447

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up