• Product name
    Anti-Somatostatin Receptor 5 antibody
    See all Somatostatin Receptor 5 primary antibodies
  • Description
    Rabbit polyclonal to Somatostatin Receptor 5
  • Host species
  • Specificity
    ab28618 recognises Somatostatin Receptor 5.
  • Tested applications
    Suitable for: IHC-P, ICC, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Somatostatin Receptor 5 aa 344-364.




Our Abpromise guarantee covers the use of ab28618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/2500.
ICC 1/5000.
WB 1/5000. Detects a band of approximately 54-63 kDa.
ICC/IF Use a concentration of 5 µg/ml.


  • Function
    Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
  • Tissue specificity
    Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SSTR5 antibody
    • Somatostatin receptor subtype 5 antibody
    • Somatostatin receptor type 5 antibody
    • SS 5R antibody
    • SS-5-R antibody
    • SS5 R antibody
    • SS5-R antibody
    • SS5R antibody
    • SSR5_HUMAN antibody
    • SST R5 antibody
    • SSTR 5 antibody
    • Sstr5 antibody
    see all


  • Anti-Somatostatin Receptor 5 antibody (ab28618) at 1 µg/ml + Brain: pituitary gland (Human) Whole Cell Lysate - adult normal tissue (ab29749) at 10 µg

    Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/3000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Observed band size: 42 kDa (why is the actual band size different from the predicted?)
    Additional bands at: 15 kDa, 20 kDa, 73 kDa. We are unsure as to the identity of these extra bands.

    Exposure time: 8 minutes

    Somatostatin Receptor 5 contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.
  • ICC/IF image of ab28618 stained MCF7 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab28618, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.


This product has been referenced in:
  • Gonzalez B  et al. Cytoplasmic expression of SSTR2 and 5 by immunohistochemistry and by RT/PCR is not associated with the pharmacological response to octreotide. Endocrinol Nutr 61:523-30 (2014). Read more (PubMed: 25008035) »
  • Liu Y  et al. Somatostatin receptor subtypes 2 and 5 are associated with better survival in operable hepatitis B-related hepatocellular carcinoma following octreotide long-acting release treatment. Oncol Lett 6:821-828 (2013). Read more (PubMed: 24137418) »

See all 7 Publications for this product

Customer reviews and Q&As

Thank you vary much for your patience while I contacted the products originator. According to the original researcher (and author of the paper that I provided), "most GPCRs are N-glycosylated proteins which accounts for 10 to 30 kDa higher molecular w...

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Thank you for your enquiry. In Charlotte's absence I am handling her enquiries. According to the original researcher (and author of the paper that Charlotte provided you with), "most GPCRs are N-glycosylated proteins which accounts for 10 to 30 kDa...

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